[HTML][HTML] Who's afraid of the X? Incorporating the X and Y chromosomes into the analysis of DNA methylation array data
… The overall distribution of DNAme on the X chromosome showed … DNA methylation profiles
of the X and Y chromosome. All plots show raw (non-normalized) data after probe filtering. A …
of the X and Y chromosome. All plots show raw (non-normalized) data after probe filtering. A …
[HTML][HTML] Methylation status of genes escaping from X-chromosome inactivation in patients with X-chromosome rearrangements
S Kawashima, A Hattori, E Suzuki, K Matsubara… - Clinical …, 2021 - Springer
… of XCI or change the total numbers of escape genes; however… with structural abnormalities
of the X chromosome has not … The DNA methylation level at each probe was converted to β …
of the X chromosome has not … The DNA methylation level at each probe was converted to β …
Epigenetic and transcriptomic consequences of excess X‐chromosome material in 47, XXX syndrome—a comparison with Turner syndrome and 46, XX females
MM Nielsen, C Trolle, S Vang… - American Journal of …, 2020 - Wiley Online Library
… In conclusion, we find an overall similar X chromosome … The expression of ncRNAs was
particular abnormal in TS … of an extra X chromosome on the genome-wide DNA methylation and …
particular abnormal in TS … of an extra X chromosome on the genome-wide DNA methylation and …
Abnormal X chromosome inactivation and tumor development
… the X chromosome is controlled by a single cis-acting total switching … X chromosome, which
prepares to initiate XCI [44]. As Xist RNA expands on the X chromosome, DNA methylation …
prepares to initiate XCI [44]. As Xist RNA expands on the X chromosome, DNA methylation …
[HTML][HTML] X chromosome dosage and the genetic impact across human tissues
M Viuff, A Skakkebæk, EB Johannsen, S Chang… - Genome Medicine, 2023 - Springer
… that the overall … of X chromosome number and sex on the DNA methylation profile, we
performed unsupervised clustering based on all X chromosomal and autosomal CpG methylation …
performed unsupervised clustering based on all X chromosomal and autosomal CpG methylation …
[HTML][HTML] Losing DNA methylation at repetitive elements and breaking bad
XG Pappalardo, V Barra - Epigenetics & chromatin, 2021 - Springer
… both gene expression and chromatin structure. Therefore, … by unscheduled methylation
correlate with abnormal repression … According to the size of the repeated unit and the total length, …
correlate with abnormal repression … According to the size of the repeated unit and the total length, …
[HTML][HTML] Aneuploidy and DNA methylation as mirrored features of early human embryo development
EN Tolmacheva, SA Vasilyev, IN Lebedev - Genes, 2020 - mdpi.com
… has two roles: it regulates gene expression and chromatin structure [9]. Abnormal
methylation due to errors in the … X chromosome monosomy is the most common genetic …
methylation due to errors in the … X chromosome monosomy is the most common genetic …
[HTML][HTML] Effects of DNA Methylation on Cancer and Aging
S Sevinç, O Erbaş - Journal of Experimental and Basic Medical Sciences, 2020 - jebms.org
… In this review, it was mentioned that abnormal DNA methylation… -term silencing of a locus in
X chromosome inactivation.[3] … A total of ~23,000 differently methylated CpG regions (Δβ≥0.1…
X chromosome inactivation.[3] … A total of ~23,000 differently methylated CpG regions (Δβ≥0.1…
Understanding the landscape of X-linked variants causing intellectual disability in females through extreme X chromosome inactivation skewing
EQ Vianna, RM Piergiorge, AP Gonçalves… - Molecular …, 2020 - Springer
… is generally mitigated by the preferential inactivation of the abnormal X chromosome [9]. …
or in the preferential inactivated X chromosome, total RNA samples from available patients …
or in the preferential inactivated X chromosome, total RNA samples from available patients …
[HTML][HTML] DNA methylation episignatures in neurodevelopmental disorders associated with large structural copy number variants: clinical implications
K Rooney, B Sadikovic - International Journal of Molecular Sciences, 2022 - mdpi.com
… more than ten times the total heritable sequence differences observed in … regulatory elements
and changes in the chromatin structure. … FRX results from abnormal expansion of the CGG …
and changes in the chromatin structure. … FRX results from abnormal expansion of the CGG …