[HTML][HTML] Regulator of chromosome condensation 2 modulates cell cycle progression, tumorigenesis, and therapeutic resistance

K Guo, C Zhao, B Lang, H Wang, H Zheng… - Frontiers in molecular …, 2021 - frontiersin.org
RCC2 overexpression promotes LUAD cell proliferation and promotes metastasis by inducing
epithelial-mesenchymal … roles in cell migration) and α5β1 integrin promotes cancer cell

[HTML][HTML] Roles of regulator of chromosome condensation 2 in cancer: Beyond its regulatory function in cell cycle

A Calderon-Aparicio, AM Bode - Oncology Reviews, 2021 - ncbi.nlm.nih.gov
… markedly enhances lung adenocarcinoma cell migration, invasion, and proliferation in vitro
by activating the epithelial-mesenchymal transition (… In breast cancer, RCC2 promotes tumor

RCC2 interacts with small GTPase RalA and regulates cell proliferation and motility in gastric cancer

P Wang, W Zhang, L Wang, W Liang, A Cai… - OncoTargets and …, 2020 - Taylor & Francis
… is related to poor prognosis in lung adenocarcinoma. Citation… that RCC2 is commonly
overexpressed in gastric cancer and … of RBC8 on cell motility by performing migration and invasion …

RCC2 contributes to tumor invasion and chemoresistance to cisplatin in hepatocellular carcinoma

Q Chen, P Jiang, B Jia, Y Liu, Z Zhang - Human Cell, 2020 - Springer
Overexpression of RCC2 is correlated with histological … the enhanced DDP sensitivity upon
downregulation of RCC2, … the mechanism for RCC2-promoted cancer progression. In the …

RCC2 promotes esophageal cancer growth by regulating activity and expression of the Sox2 transcription factor

A Calderon-Aparicio, H Yamamoto, H De Vitto… - Molecular Cancer …, 2020 - AACR
… , RCC2 also has a role in cell migration (8). RCC2 is overexpressed in a variety of different
tumor … In breast cancer, RCC2 promotes tumor progression by activating Wnt pathway through …

[HTML][HTML] Comprehensive analysis of prognostic value and immune infiltration of Regulator of Chromosome Condensation 2 in lung adenocarcinoma

H Lin, G Lin, L Lin, J Yang, D Yang, Q Lin, Y Xu… - … of Cancer, 2024 - ncbi.nlm.nih.gov
… level of RCC2 showed obvious overexpression in LUAD … between RCC2 expression level
and LUAD cell migration and … promotes cell proliferation, epithelial-mesenchymal transition

RCC2 promotes prostate cancer cell proliferation and migration through Hh/GLI1 signaling pathway and cancer stem-like cells

S Wang, Z Lei, W Liu, J Xiong, Y Shi, L Yang, Q Gao… - Biology Direct, 2023 - Springer
… greatly enhanced after RCC2 overexpression, while the RCC2 … as an oncogene to promote
cancer progression, tumorigenesis… tumorigenesis via promoting cell migration and inhibiting …

A pan‑cancer analysis of RCC2 and its interaction with HMGA2 protein in an in vitro model of colorectal cancer cells

G Gu, Y Wang, Y Shen, Y Ma… - Experimental and …, 2022 - spandidos-publications.com
RCC2 overexpression promotes cancer malignant … pathways and epithelial-mesenchymal
transition (EMT) (9). In … RCC2 promotes tumor metastasis by interacting with Rac1 and …

RCC2 Expression Stimulates ER‐Positive Breast Tumorigenesis

W Wang, B Xu, Z Zhang, K Fang… - Journal of Oncology, 2020 - Wiley Online Library
… Pang et al. found that overexpression of RCC2 enhances cell motility and promotes tumor
metastasis in lung adenocarcinoma by inducing epithelial-mesenchymal transition (EMT) [7]. …

miR-124 and miR-203 synergistically inactivate EMT pathway via coregulation of ZEB2 in clear cell renal cell carcinoma (ccRCC)

J Chen, Y Zhong, L Li - Journal of Translational Medicine, 2020 - Springer
… -overexpression in 786-O cells, implying that the tumorcells and stromal cells is reduced,
intercellular interactions are reduced, and cell migration and exercise capacity are enhanced