MicroRNA 320, an anti-oncogene target miRNA for cancer therapy

Y Liang, S Li, L Tang - Biomedicines, 2021 - mdpi.com
… of BMI1 proto-oncogene, polycomb ring finger (BMI1), a … miR-320 expression via interaction
with BMI 1 [29]. Therefore, a TWIST1… that overexpression of hsa-miR-320e suppressed tumor

Interpreting the molecular mechanisms of RBBP4/7 and their roles in human diseases

Y Zhan, A Yin, X Su, N Tang… - International …, 2024 - spandidos-publications.com
… of several protein complexes, such as polycomb repressive … have complex roles in cervical
cancer and may be potential … overexpression induces cell death in LNCaP prostate cancer

The role of miRNAs in the regulation of endometrial cancer invasiveness and metastasis—a systematic review

K Klicka, TM Grzywa, A Klinke, A Mielniczuk… - Cancers, 2021 - mdpi.com
… virus insertion region-1 (BMI-1), Transcription Factor 3 (E2F3), … EZH2 is the enzymatic catalytic
subunit of the polycomb-… It is overexpressed in many types of cancer, including EC [208], …

miRNAs as modulators of cholesterol in breast cancer stem cells: An approach to overcome drug resistance in cancer

B Monchusi, M Kaur - Current drug targets, 2022 - ingentaconnect.com
… modifier that belongs to the Polycomb Group (PcG) of the … hsa-miR-43a-5p overexpression
to lead to an increase in ABCA1/… Hedgehog signaling and Bmi-1 [78] regulate self-renewal of …

ABCG2 Gene and ABCG2 Protein Expression in Colorectal Cancer—In Silico and Wet Analysis

A Sałagacka-Kubiak, D Zawada, L Saed… - International Journal of …, 2023 - mdpi.com
… , score = 0.880), polycomb complex protein BMI-1 (BMI1, score = … of ABCG2 mRNA and
protein overexpression in multidrug … Another important marker of colorectal CSCs is BMI-1. Both …

Anticancer perspectives of genistein: a comprehensive review

H Naeem, U Momal, M Imran, M Shahbaz… - … Journal of Food …, 2023 - Taylor & Francis
Overexpression of HER2 has not been proven to be associated … downregulate the polycomb
group (PcG) proteins BMI 1 and EZH2… of HeLa cells in human cervical cancer cells in a dose-…

[HTML][HTML] Chromobox 4 facilitates tumorigenesis of lung adenocarcinoma through the Wnt/β-catenin pathway

Z Wang, Z Fang, G Chen, B Liu, J Xu, F Li, F Li, H Liu… - Neoplasia, 2021 - Elsevier
Polycomb group (PcG) proteins are known as master … stable CBX4-overexpressed cell
models in 2 human LUAD cell … in human LUAD samples at both the mRNA and protein levels, …

MYSM1 inhibits human colorectal cancer tumorigenesis by activating miR-200 family members/CDH1 and blocking PI3K/AKT signaling

X Chen, W Wang, Y Li, Y Huo, H Zhang, F Feng… - … & Clinical Cancer …, 2021 - Springer
… H2AK119ub1-mediated repression of polycomb target genes … For example, BMI1 is
overexpressed and promotes cancer … (THCA), ovarian serous cystadenocarcinoma (OV) and …

Cancer-associated dysregulation of sumo regulators: Proteases and ligases

N Lara-Ureña, V Jafari… - International Journal of …, 2022 - mdpi.com
protein RanBP2 and the Polycomb Repressive Complex 2 … MYC is also overexpressed
in one third of breast cancers [… In cervical cancer samples, as well as in cell lines associated …

Induction of Oxidative Stress: A Promising Approach in Female Gynecological Cancer Therapeutic Arsenal

C Amalinei, RA Balan, L Lozneanu - … of Oxidative Stress in Cancer …, 2022 - Springer
… for cervical cancer, there are other cofactors responsible for … of ovulation or in the context
of endometriosis), lactic acidosis, … leads to E6 and E7 overexpression, which represents a …