Mitochondrial fatty acid utilization increases chromatin oxidative stress in cardiomyocytes
I Menendez-Montes, S Abdisalaam… - Proceedings of the …, 2021 - National Acad Sciences
… of the adult mammalian heart to regenerate following injury. … increases chromatin ROS and
chromatin oxidation could at … of FAO in the adult heart reduces oxidative DNA damage (7). …
chromatin oxidation could at … of FAO in the adult heart reduces oxidative DNA damage (7). …
Oxidation of sperm nucleus in mammals: A physiological necessity to some extent with adverse impacts on oocyte and offspring
… DNA are sensitive to oxidative damage, a summary of the most recent results concerning the
oxidation of sperm DNA … sensitive to oxidation in the weakly condensed chromatin of human …
oxidation of sperm DNA … sensitive to oxidation in the weakly condensed chromatin of human …
Oxidative stress is associated with telomere interaction impairment and chromatin condensation defects in spermatozoa of infertile males
B Berby, C Bichara, A Rives-Feraille, F Jumeau… - Antioxidants, 2021 - mdpi.com
… whether oxidative stress has an impact on sperm nuclear alterations, especially on chromatin
… packaging by perturbing the non-random ordering of mammalian chromosome in sperm …
… packaging by perturbing the non-random ordering of mammalian chromosome in sperm …
Oxidation of sperm DNA and male infertility
… oxidative stress on the sperm genome go well beyond DNA … sperm nucleus especially upon
chromatin remodeling and histone … A unique aspect of the chromatin structure of mammalian …
chromatin remodeling and histone … A unique aspect of the chromatin structure of mammalian …
Autolysosomal degradation of cytosolic chromatin fragments antagonizes oxidative stress–induced senescence
X Han, H Chen, H Gong, X Tang, N Huang… - Journal of Biological …, 2020 - ASBMB
… Oxidative stress-induced DNA damage, the senescence-associated secretory … stress,
we show that stress-induced DNA damage provokes the SASP largely via cytosolic chromatin …
we show that stress-induced DNA damage provokes the SASP largely via cytosolic chromatin …
Sperm chromatin assessment
A Agarwal, R Sharma - Textbook of assisted reproductive …, 2023 - taylorfrancis.com
… In many mammals, spermatogenesis leads to the production of highly homogenous … ,
and oxidative stress, along with other clinical and environmental risk factors [31]. Sperm …
and oxidative stress, along with other clinical and environmental risk factors [31]. Sperm …
Molecular aspects of senescence and organismal ageing—DNA damage response, telomeres, inflammation and chromatin
N Sławińska, R Krupa - International journal of molecular sciences, 2021 - mdpi.com
… In mammalian cells, ectopic insertion of … to oxidative stress. It was caused by the relocation
of SIRT1 to double-strand breaks that came into existence in the wake of the oxidative stress. …
of SIRT1 to double-strand breaks that came into existence in the wake of the oxidative stress. …
[HTML][HTML] The genomics of oxidative DNA damage, repair, and resulting mutagenesis
AR Poetsch - Computational and structural biotechnology journal, 2020 - Elsevier
… Instead, oxidative DNA damage distribution at the level of chromatin domains is dominated
… This type of oxidative stress occurs directly next to the DNA. An effect on gene regulation …
… This type of oxidative stress occurs directly next to the DNA. An effect on gene regulation …
DNA damage and oxidative stress in human cells infected by Trypanosoma cruzi
PTV Florentino, D Mendes, FNL Vitorino… - PLoS …, 2021 - journals.plos.org
… As DNA base oxidation and chromatin proteins appear to be carbonylated soon after …
Notably, BNZ decreases mammalian cell DNA lesions derived from oxidative injury. This result led …
Notably, BNZ decreases mammalian cell DNA lesions derived from oxidative injury. This result led …
[HTML][HTML] DNA damage and the aging epigenome
A Siametis, G Niotis, GA Garinis - Journal of Investigative Dermatology, 2021 - Elsevier
… In mammalian cells, chromatin fibers reversibly alternate between compact and relaxed
structural states. In doing so, the underlying … Oxidative stress and antioxidant defense …
structural states. In doing so, the underlying … Oxidative stress and antioxidant defense …