Characterization of metabolic patterns in mouse oocytes during meiotic maturation
L Li, S Zhu, W Shu, Y Guo, Y Guan, J Zeng, H Wang… - Molecular cell, 2020 - cell.com
… profile of mouse oocytes during in vivo maturation by isolating … to metabolic pathways such
as glutathione/carbon/pyruvate … during meiotic maturation (ie, oxidative phosphorylation and …
as glutathione/carbon/pyruvate … during meiotic maturation (ie, oxidative phosphorylation and …
Metabolic control of oocyte development
S Zhu, Q Wang - Biology of Reproduction, 2022 - academic.oup.com
… mouse oocytes during in vivo maturation, depicting the global metabolic patterns in oocytes.
… The meiotic defects in mouse oocyte with pyruvate dehydrogenase E1 subunit alpha 1 (also …
… The meiotic defects in mouse oocyte with pyruvate dehydrogenase E1 subunit alpha 1 (also …
Reprogramming of glucose metabolism of cumulus cells and oocytes and its therapeutic significance
S Imanaka, H Shigetomi, H Kobayashi - Reproductive Sciences, 2022 - Springer
… Both aerobic glycolysis and oxidative phosphorylation (OXPHOS) … , pyruvate and lactate
are required as an energy source for 2-cell mouse embryos to develop into blastocysts in vitro […
are required as an energy source for 2-cell mouse embryos to develop into blastocysts in vitro […
Characterization of carbohydrate metabolism in in vivo-and in vitro-grown and matured mouse antral follicles
AC Herta, L von Mengden, N Akin… - Biology of …, 2022 - academic.oup.com
… boost of pyruvate and lactate uptake in cumulus cells in vivo, … activities, while in vitro, the
metabolic upregulation in all the … [57–59], the oocyte still relies on oxidative phosphorylation (…
metabolic upregulation in all the … [57–59], the oocyte still relies on oxidative phosphorylation (…
Redox Regulation and Oxidative Stress in Mammalian Oocytes and Embryos Developed In Vivo and In Vitro
… metabolism and away from oxidative phosphorylation [50]. … over 5 days in the mouse in
vivo. The maternal reproductive … a switch in energy source from pyruvate to glucose [97,98]. In …
vivo. The maternal reproductive … a switch in energy source from pyruvate to glucose [97,98]. In …
α‐Ketoglutarate Improves Meiotic Maturation of Porcine Oocytes and Promotes the Development of PA Embryos, Potentially by Reducing Oxidative Stress through the …
Q Chen, L Gao, J Li, Y Yuan, R Wang… - Oxidative Medicine …, 2022 - Wiley Online Library
… in vitro maturation (IVM) on the maturation of porcine oocytes … D-glucose, 0.91 mm sodium
pyruvate, 0.57 mm cysteine, 75 μg/… to the oxidative phosphorylation of oocytes. Therefore, we …
pyruvate, 0.57 mm cysteine, 75 μg/… to the oxidative phosphorylation of oocytes. Therefore, we …
Metabolic co-dependence of the oocyte and cumulus cells: essential role in determining oocyte developmental competence
… formation and supply of pyruvate to the oocyte for ATP production. … oocyte lipid metabolism
for oocyte oxidative phosphorylation … that involves the maturation of oocytes in vitro prior to …
for oocyte oxidative phosphorylation … that involves the maturation of oocytes in vitro prior to …
Energy metabolism of the equine cumulus oocyte complex during in vitro maturation
… pyruvate results in the highest maturation rates for mouse … We also examined the metabolic
effect of including pyruvate to … of glycolytic and oxidative metabolism in equine oocytes during …
effect of including pyruvate to … of glycolytic and oxidative metabolism in equine oocytes during …
Effects of glucose metabolism pathways on nuclear and cytoplasmic maturation of pig oocytes
J Wen, GL Wang, HJ Yuan, J Zhang, HL Xie, S Gong… - Scientific Reports, 2020 - nature.com
… , pyruvate and lactate was compared between pig and mouse … in CCs is essential for oocyte
cytoplasmic maturation and that … used for in vitro maturation of mouse oocytes were exactly …
cytoplasmic maturation and that … used for in vitro maturation of mouse oocytes were exactly …
Abnormal early folliculogenesis due to impeded pyruvate metabolism in mouse oocytes
K Tanaka, Y Hayashi, A Takehara… - Biology of …, 2021 - academic.oup.com
… [15], suggesting enhanced oxidative phosphorylation (OXPHOS) in developing oocytes. In …
pyruvate metabolism in folliculogenesis up to the secondary follicle in culture as well as in vivo…
pyruvate metabolism in folliculogenesis up to the secondary follicle in culture as well as in vivo…