[HTML][HTML] New perspectives on the therapeutic potential of quercetin in non-communicable diseases: Targeting Nrf2 to counteract oxidative stress and inflammation
L Zhang, LY Xu, F Tang, D Liu, XL Zhao… - Journal of …, 2024 - Elsevier
… In conclusion, Nrf2 activation plays a crucial role in protecting muscles from inflammation-induced
damage and oxidative stress. Nrf2 regulates mitochondrial function, cellular redox …
damage and oxidative stress. Nrf2 regulates mitochondrial function, cellular redox …
Nrf2 and oxidative stress: A general overview of mechanisms and implications in human disease
V Ngo, ML Duennwald - Antioxidants, 2022 - mdpi.com
… studied in the disease contexts. This review aims to provide the reader with a general overview
of oxidative stress and Nrf2, including basic mechanisms of Nrf2 activation and regulation…
of oxidative stress and Nrf2, including basic mechanisms of Nrf2 activation and regulation…
Targeting oxidative stress in disease: promise and limitations of antioxidant therapy
HJ Forman, H Zhang - Nature Reviews Drug Discovery, 2021 - nature.com
… evaluated as antioxidants have exhibited therapeutic potential in preclinical studies, …
oxidative stress, redox signalling and disease, the mechanisms through which oxidative stress can …
oxidative stress, redox signalling and disease, the mechanisms through which oxidative stress can …
Advances and challenges in therapeutic targeting of NRF2
AT Dinkova-Kostova, IM Copple - Trends in pharmacological sciences, 2023 - cell.com
… Activation of the transcription factor nuclear factor erythroid 2-related factor 2 (NRF2) is
emerging as an attractive therapeutic approach to counteract oxidative stress, inflammation, and …
emerging as an attractive therapeutic approach to counteract oxidative stress, inflammation, and …
Impaired antioxidant KEAP1-NRF2 system in amyotrophic lateral sclerosis: NRF2 activation as a potential therapeutic strategy
S Bono, M Feligioni, M Corbo - Molecular Neurodegeneration, 2021 - Springer
… Although oxidative damage in biological systems has in the past been completely attributed
to ROS, it is becoming increasingly clear that also reactive nitrogen species (RNS) and …
to ROS, it is becoming increasingly clear that also reactive nitrogen species (RNS) and …
A perspective on Nrf2 signaling pathway for neuroinflammation: a potential therapeutic target in Alzheimer's and Parkinson's diseases
… So far, we discussed different aspects of Nrf2 signaling pathway in oxidative stress and
inflammation in neurodegenerative diseases, therefore, it is also worthwhile to discuss …
inflammation in neurodegenerative diseases, therefore, it is also worthwhile to discuss …
The therapeutic potential of Nrf2 inducers in chronic pain: Evidence from preclinical studies
YQ Zhou, W Mei, XB Tian, YK Tian, DQ Liu… - … & therapeutics, 2021 - Elsevier
… Considering the complexity of oxidative stress, interventions such as administration of Nrf2
inducers might be too simplistic. A better understanding of redox biology under chronic pain …
inducers might be too simplistic. A better understanding of redox biology under chronic pain …
Bioactive compounds in oxidative stress-mediated diseases: targeting the NRF2/ARE signaling pathway and epigenetic regulation
M Thiruvengadam, B Venkidasamy, U Subramanian… - Antioxidants, 2021 - mdpi.com
… as a promising target against oxidative stress-mediated diseases like diabetes, fibrosis, …
on the NRF2/ARE signaling pathway and its role in oxidative stress-mediated diseases. …
on the NRF2/ARE signaling pathway and its role in oxidative stress-mediated diseases. …
[HTML][HTML] Regulation of immunomodulatory networks by Nrf2-activation in immune cells: Redox control and therapeutic potential in inflammatory diseases
… the burden of these diseases, nuclear factor erythroid 2-related factor 2 (Nrf2) has emerged
… in cellular defense against metabolic and oxidative stress, Nrf2's role in modulating the …
… in cellular defense against metabolic and oxidative stress, Nrf2's role in modulating the …
Current evidence to support the therapeutic potential of flavonoids in oxidative stress-related dermatoses
D Xian, M Guo, J Xu, Y Yang, Y Zhao, J Zhong - Redox report, 2021 - Taylor & Francis
… only greatly benefiting people health and dietary ingredients, but also lowering the risk of
health problems, like age-related degenerative diseases, cardiovascular disease, OS-related …
health problems, like age-related degenerative diseases, cardiovascular disease, OS-related …