… protected mitochondrial function by modulating SIRT3/PARP-1 pathway, contributing to the
inhibition of cardiac … Moreover, a recent study demonstrated that diabetic cardiomyopathy in …

… In conclusion, liraglutide can protect cardiomyocytes and improve cardiac function, and …
Therefore, we speculated that liraglutide could inhibit the expression of cardiac PARP-1 and …

… of PARP activation has been shown to alter heart function in … Citation28 PARP-1 inhibition
led to increased Sirt1 and … -1 activity and protects the kidney under diabetic conditions. …

… inhibition and siRNA silencing of PARP-1 protected … to decreased activation of the NAD +
-SIRT1-PGC-1α-UCP2 axis … endothelial dysfunction in diabetes wherein PARP-1 is responsible …

… A negative role of the PARP-1 hyperactivation in cardiac … These mice are better protected
from diabetic and septic … of diabetic complications caused by increased PARP-1 activity, …

… by RGFP966 could protect against DM-induced cardiac … role in DCM through the SIRT1/PGC-1α
signaling pathway (37). … mice, suggesting that the effect of the SIRT1/FOXO1/Rab7 axis …

… which is known noticeably to protect tissues from oxidative injury. … of the antioxidative pathway,
such as SIRT1/PGC-1α, SIRT1-Nrf2, … of vitamin D acting on renin-angiotensin axis in DN. …

… NF-κB-p65 is another target of SIRT1 in protecting against diabetic cardiomyopathy. … diabetic
hearts: potential role of NO/SIRT1/PGC-1α signaling. American journal of physiology heart …

… SIRT3 could inhibit cardiac hypertrophy by repressing PARP-1 activation in cardiomyocytes.
… /reperfusion injury, atherosclerosis and cardiovascular complications of diabetes [40–42]. …

… SIRT1/PGC-1α axis, which plays an important role in protecting myocardial tissue from
diabetic … In the heart of diabetic rats, the mRNA expression level of parp-1 gene was 2.8 times …