[HTML][HTML] Analyses of non-coding somatic drivers in 2,658 cancer whole genomes
… The discovery of drivers of cancer … driver point mutations and structural variants in non-coding
regions across 2,658 genomes from the Pan-Cancer Analysis of Whole Genomes (PCAWG…
regions across 2,658 genomes from the Pan-Cancer Analysis of Whole Genomes (PCAWG…
[HTML][HTML] Genomic basis for RNA alterations in cancer
PCAWG Transcriptome Core Group Calabrese Claudia … - Nature, 2020 - nature.com
… types by the PCAWG Transcriptome Working Group 5 , providing … We found three separate
structural variants in the same … ) cancer census genes or PCAWG driver genes that are both …
structural variants in the same … ) cancer census genes or PCAWG driver genes that are both …
[HTML][HTML] Decoding human cancer with whole genome sequencing: a review of PCAWG Project studies published in February 2020
S Giunta - Cancer and Metastasis Reviews, 2021 - Springer
… the work, the PCAWG Consortium failed to identify any driver … [10], how structural variants
affect the transcriptome [22] and … ones identified from the PCAWG initial analysis. Notably, this …
affect the transcriptome [22] and … ones identified from the PCAWG initial analysis. Notably, this …
[HTML][HTML] Pan-cancer analysis of whole genomes
Nature, 2020 - nature.com
… Chromothripsis, in which many clustered structural variants arise in a … A Technical Working
Group implemented the informatics … in PCAWG tumours that have high confidence to be driver …
Group implemented the informatics … in PCAWG tumours that have high confidence to be driver …
Pan-cancer analysis of whole genomes
T Underwood - Nature, 2020 - eprints.soton.ac.uk
… Chromothripsis, in which many clustered structural variants arise in a … A Technical Working
Group implemented the informatics … in PCAWG tumours that have high confidence to be driver …
Group implemented the informatics … in PCAWG tumours that have high confidence to be driver …
[HTML][HTML] Pan-cancer analysis of whole genomes identifies driver rearrangements promoted by LINE-1 retrotransposition
B Rodriguez-Martin, EG Alvarez, A Baez-Ortega… - Nature …, 2020 - nature.com
… PCAWG Consortium 21 (see Methods). Our analyses identify patterns and mutational
mechanisms of structural variation in … by the PCAWG Evolution and Heterogeneity Working Group, …
mechanisms of structural variation in … by the PCAWG Evolution and Heterogeneity Working Group, …
[HTML][HTML] Germline structural variation globally impacts the cancer transcriptome including disease-relevant genes
F Chen, Y Zhang, FJ Sedlazeck, CJ Creighton - Cell Reports Medicine, 2024 - cell.com
… Improved structural variant interpretation for hereditary cancer susceptibility using long-read …
To explore germline structural variation in cancer, we referred to the PCAWG dataset of …
To explore germline structural variation in cancer, we referred to the PCAWG dataset of …
[HTML][HTML] Patterns of somatic structural variation in human cancer genomes
… Mutations that arise in somatic cells are the driving force of … somatically acquired structural
variants in this analysis, and … the Technical Working Group of the PCAWG Consortium and …
variants in this analysis, and … the Technical Working Group of the PCAWG Consortium and …
[HTML][HTML] Genome-wide interrogation of structural variation reveals novel African-specific prostate cancer oncogenic drivers
… and PCAWG cohorts [6], while our new method highlighted 18 additional potential driver
genes… Through direct ethnic-based comparative analysis using a single technical and informatic …
genes… Through direct ethnic-based comparative analysis using a single technical and informatic …
[HTML][HTML] High-coverage whole-genome analysis of 1220 cancers reveals hundreds of genes deregulated by rearrangement-mediated cis-regulatory alterations
… In this present study, we utilize the PCAWG datasets in order … impact of somatic structural
variants on gene expression … to acknowledge the PCAWG Transcriptome Working Group (…
variants on gene expression … to acknowledge the PCAWG Transcriptome Working Group (…