Pan-genome is an approach that contributes to the research of bacterial pathogenesis. From
the sequencing data, one can thoroughly study each region of the genome, contributing with
unpublished information. Since 2005, with the era of new sequencers, the speed, ease, and
reliability of data has been increasing and with them the number of bacterial genomes
deposited in public databases. Pan-genome studies can be applied with different goals,
such as taxonomy, reverse vaccinology, gene variation, and pathogenesis, among others …