… metabolic pathways and rely on metabolic scavenging pathways such as autophagy and
macropinocytosis. Here, we review the metabolic … tumours rewire their metabolism and use …

… Pancreatic cancer (PC) has one of the highest fatality rates … Metabolic reprogramming is
among the hallmarks of cancer … subtypes, the identification of metabolic subtypes in PC could aid …

… Pancreatic ductal adenocarcinoma (PDAC) is characterized by its unique metabolic …
interaction with the host cells in the tumor microenvironment. Understanding these properties and …

… By keeping glycolysis over oxidative phosphorylation, tumor cells can conserve pyruvate
to build the new nucleic acids needed for cell growth and the carbon skeleton needed for …

… metabolism in Kras-mutant pancreatic cancer cells are closely interlinked by some of the
downstream anabolic pathways, and depend on each other to promote tumour aggressiveness …

… a metabolic requirement for pancreatic tumor immune evasion. Mechanistically, autophagy
protects cancer cells … Altogether, this resource provides metabolic dependencies arising from …

… in pancreatic cancer with a … cancer cells generate lactate, which is extruded to the extracellular
environment by the lactate transporter MCT4. Lactate is then taken up by oxidative cancer …

… subtypes in pancreatic cancer and discuss how CAFs shape cancer cell metabolism through
… cells are in continuous need for energetic fuel and building blocks to support their superior …

… suggest metabolic changes due to subclinical disease may occur up to … metabolism within
PDAC cells such that aspartate is synthesised from glutamine-derived glutamate to generate …

… cancer growth. This study provides insights into the metabolic regulatory circuit of pancreatic
cancer … signals in interfering with this metabolic rewiring to hinder cancer development. …