Chronic obstructive pulmonary disease: management of chronic disease

A Braddy-Green, M MacLeod, FM Conway, JP Allinson… - Medicine, 2023 - Elsevier
Reversibility can be present but incomplete. Other causes of … concomitant asthma and
elevated serum eosinophil count may … An arterial partial pressure of oxygen (PaO 2 ) <7.3 kPa on …

Efficacy and safety of once-daily single-inhaler triple therapy for mild-to-moderate chronic obstructive pulmonary disease: a study protocol for a randomised and …

K Takahashi, T Kawayama… - … Open Respiratory …, 2023 - bmjopenrespres.bmj.com
… Mean change from baseline in the reversibility of FEV1 at 12 … We will assess blood
eosinophil counts at every visit to … of bacterial pneumonia, sputum mycobacteria, and titre of anti-…

[HTML][HTML] The Complex Interplay: Unfolding the Mechanisms of Chronic Obstructive Pulmonary Disease

PG Okwute, AM Mofolorunso, GO Oluwatunase… - 2024 - intechopen.com
… The diagnosis of reversible airflow obstruction indicates that … to contemplate the utilization
of inhaled corticosteroids (ICS). … of eosinophils in the airway tissue and/or in sputum (mucus …

Biologics in Asthma and Chronic Obstructive Pulmonary Disorder.

M Cazzola, MG Matera, L Calzetta… - … Pulmonary Diseases, 2022 - search.ebscohost.com
… fixed airflow obstruction with high bronchodilator reversibility … in the sputum are linked to the
number of sputum eosinophils.[ 45] … -to-severe COPD who are on inhaled maintenance triple …

Morbidity and mortality associated with chronic obstructive pulmonary disease (COPD)

RC Richie - Journal of Insurance Medicine, 2023 - meridian.allenpress.com
… asthma whose airflow obstruction is completely reversible are not … a gradual change from
an eosinophilic inflammatory cascade to a … Airflow limitation that is irreversible or only partially

[PDF][PDF] Systemic medications in chronic obstructive pulmonary disease: Use and outcomes

N Roche - Clinics in Chest Medicine, 2020 - Elsevier
airflow obstruction and emphysema is the consequence of a … the systemic component of
COPD, inhaled treatments may not … neutrophilic and eosinophilic airways inflammation, which …

[HTML][HTML] Mechanisms, pathophysiology and currently proposed treatments of chronic obstructive pulmonary disease

SO Rodrigues, CMC Cunha, GMV Soares, PL Silva… - Pharmaceuticals, 2021 - mdpi.com
… by progressive airflow limitation that is not fully reversible, … COPD patients have increased
neutrophil numbers in sputum … LJ-529, a partial peroxisome proliferator-activated gamma …

Increased serum levels of matrix-metalloproteinase-9, cyclo-oxygenase-2 and prostaglandin E-2 in patients with chronic obstructive pulmonary disease (COPD)

AK Verma, AK Pandey, A Singh, S Kant… - Indian Journal of Clinical …, 2022 - Springer
… which is not fully reversible. Inflammation as well as … epithelial cells, neutrophils,
eosinophils, mast cells and alveolar … In addition, by partially protecting against allergen-induced …

Asthma-chronic obstructive pulmonary disease overlap syndrome

MF Mart, RS Peebles Jr - Current opinion in immunology, 2020 - Elsevier
… on spirometry that is, at least in part, reversible with … , or laboratory evidence of eosinophilia
in the blood or sputum, in … In this study, higher levels of eosinophils at screening were …

Techniques to evaluate asthma

GB Lee, KL Tison - Allergic and Immunologic Diseases, 2022 - Elsevier
… Peripheral blood eosinophils and fractional exhaled nitric oxide … Asthma is a prevalent
chronic obstructive lung disease … is at least partially reversible after bronchodilator medication. …