Airborne particulate matter induces oxidative damage, DNA adduct formation and alterations in DNA repair pathways
EM Quezada-Maldonado, Y Sánchez-Pérez… - Environmental …, 2021 - Elsevier
… increase or accelerate the acquisition of mutations, mostly if … DNA damage, which is
possibly due to their mutagenic … with DNA damage and over this limit, inhibition of DNA repair …
possibly due to their mutagenic … with DNA damage and over this limit, inhibition of DNA repair …
[HTML][HTML] Inflammation response, oxidative stress and DNA damage caused by urban air pollution exposure increase in the lack of DNA repair XPC protein
N de Oliveira Alves, GM Pereira, M Di Domenico… - Environment …, 2020 - Elsevier
… It is long known that exposure to particulate matter less than … a powerful mutagenic aromatic
found in the airborne particles … been shown to inhibit the removal of DNA damage by the …
found in the airborne particles … been shown to inhibit the removal of DNA damage by the …
Effects of DNA Damage and Oxidative Stress in Human Bronchial Epithelial Cells Exposed to PM2.5 from Beijing, China, in Winter
BY Niu, WK Li, JS Li, QH Hong… - International Journal of …, 2020 - mdpi.com
… In recent years, air pollution particulate matter (PM), … cells will present DNA damage responses
(DDR) such as DNA mutation, … to DNA damage sites and promotes DNA damage repair in …
(DDR) such as DNA mutation, … to DNA damage sites and promotes DNA damage repair in …
Combined exposure to formaldehyde and PM2. 5: Hematopoietic toxicity and molecular mechanism in mice
… a link between exposure to particulate matter and a higher risk of … inhibition, both indicated
that DNA damage might be caused by two factors: on one hand, the increase of DNA damage …
that DNA damage might be caused by two factors: on one hand, the increase of DNA damage …
[HTML][HTML] Particulate matter causes telomere shortening and increase in cellular senescence markers in human lung epithelial cells
J Chang-Chien, JL Huang, HJ Tsai, SL Wang… - Ecotoxicology and …, 2021 - Elsevier
… -dependent kinase inhibitors (CDKi), … DNA damage is not repaired at cell cycle checkpoint,
the induced p21 binds to the PCNA, resulting in the inactivation of PCNA-dependent DNA …
the induced p21 binds to the PCNA, resulting in the inactivation of PCNA-dependent DNA …
Nickel nanoparticle-induced cell transformation: involvement of DNA damage and DNA repair defect through HIF-1α/miR-210/Rad52 pathway
Y Mo, Y Zhang, Y Zhang, J Yuan, L Mo… - Journal of …, 2021 - Springer
… increases recombination frequencies following exposure to γ-rays [46]. A previous study
showed that traffic fine particulate matter (PM … of mutation by DNA sequencing. Colony PCR and …
showed that traffic fine particulate matter (PM … of mutation by DNA sequencing. Colony PCR and …
Inhibitory activities of ononin on particulate matter-induced oxidative stress
… In the current study, western blotting showed an increase in the conversion of LC3-I to LC3-…
In addition, our results showed that ononin significantly inhibited PM2.5-induced decreases …
In addition, our results showed that ononin significantly inhibited PM2.5-induced decreases …
Particle-induced oxidative damage by indoor size-segregated particulate matter from coal-burning homes in the Xuanwei lung cancer epidemic area, Yunnan …
X Feng, L Shao, C Xi, T Jones, D Zhang, K BéruBé - Chemosphere, 2020 - Elsevier
… The DNA damage rate from the airborne particles in the high … stress in the respiratory system
increases the production of … the DNA damage rate, implying this element might inhibit the …
increases the production of … the DNA damage rate, implying this element might inhibit the …
Distribution, sources, risks, and vitro DNA oxidative damage of PM2. 5-bound atmospheric polycyclic aromatic hydrocarbons in Urumqi, NW China
W Wang, X Ding, Y Turap, Y Tursun, A Abulizi… - Science of The Total …, 2020 - Elsevier
… 100 μg/mL increase. This shows that the average rate of increase in DNA damage is
approximately 2.8, indicating a linear relationship between PM 2.5 and DNA damage. Our results …
approximately 2.8, indicating a linear relationship between PM 2.5 and DNA damage. Our results …
Reactive oxygen species-mediated cellular genotoxic stress is involved in 1-nitropyrene-induced trophoblast cycle arrest and fetal growth restriction
B Wang, S Xu, X Lu, L Ma, L Gao, SY Zhang, R Li… - Environmental …, 2020 - Elsevier
… particulate matter (PM2.5). Our recent study demonstrated that gestational 1-NP exposure
caused placental proliferation inhibition … , oxidative DNA damage leads to DNA double-strand …
caused placental proliferation inhibition … , oxidative DNA damage leads to DNA double-strand …