… with bone metastases from solid tumors suffer … a bone-targeted treatment (17, 18). SREs
can occur quite early and indeed can be the presenting event in a patient with bone metastasis. …

… solid malignancy originating outside of the bone and joints between January 1, 2010 and
December 31, 2016. The SEER database includes information on cancer incidence, treatment, …

… common primary cancer with de novo bone metastases are cancers of … Finally, information
regarding treatment regimens were not … Any impact that treatment has on survival could not be …

… insights into the bone metastatic process of various solid tumors, including pediatric cancers.
We … In particular, we discuss the role of the bone marrow microenvironment in the attraction, …

… involved in the pathogenesis of prostate cancer bone metastases because coexpression of
… data from 5543 patients with advanced solid tumors and bone metastases, treated with either …

… LOX expression can be induced under hypoxia, which is frequently observed in almost
all solid tumors, and LOX can thus be used as a biomarker for premalignant changes during …

… common sites of metastasis for many solid tumors. Once cancer cells colonize in the bone,
it … The AZURE trial showed that with treatment, incidence of bone metastasis was reduced. …

… Among the intravenous agents, zoledronic acid is approved for the treatment of bone
metastases in solid tumors and multiple myeloma, and pamidronate is approved for patients with …

… Zoledronic acid versus placebo in the treatment of skeletal metastases in patients with lung
cancer and other solid tumors: a phase III, double-blind, randomized trial—the Zoledronic …

… evaluation of BM from different solid tumours, including DTC [23]… malignant bone marrow
disorders with respect to the normal … treatment or be used alone, in case of refractory bone pain, …