How I treat pediatric acute myeloid leukemia
JE Rubnitz, GJL Kaspers - Blood, The Journal of the American …, 2021 - ashpublications.org
… Treatment outcomes for pediatric patients with acute myeloid leukemia (AML) have continued
to lag behind outcomes reported for children with acute lymphoblastic leukemia (ALL), in …
to lag behind outcomes reported for children with acute lymphoblastic leukemia (ALL), in …
Cytogenetics of pediatric acute myeloid leukemia: a review of the current knowledge
J Quessada, W Cuccuini, P Saultier, M Loosveld… - Genes, 2021 - mdpi.com
… Pediatric acute myeloid leukemia is a rare and … current WHO classification of acute myeloid
leukemia, where there … an updated review of cytogenetics in pediatric AML, describing well-…
leukemia, where there … an updated review of cytogenetics in pediatric AML, describing well-…
Pediatric acute myeloid leukemia—past, present, and future
D Reinhardt, E Antoniou, K Waack - Journal of clinical medicine, 2022 - mdpi.com
… This review reports about the main steps of development in pediatric acute myeloid
leukemia (AML) concerning diagnostics, treatment, risk groups, and outcomes. Finally, a …
leukemia (AML) concerning diagnostics, treatment, risk groups, and outcomes. Finally, a …
A new genomic framework to categorize pediatric acute myeloid leukemia
… Recent studies on pediatric acute myeloid leukemia (pAML) have revealed pediatric-specific
driver alterations, many of which are underrepresented in the current classification schemas…
driver alterations, many of which are underrepresented in the current classification schemas…
Pediatric relapsed acute myeloid leukemia: a systematic review
AE Hoffman, LJ Schoonmade… - Expert review of …, 2021 - Taylor & Francis
Introduction: Pediatric relapsed acute myeloid leukemia (AML) remains lethal in the majority
of cases, despite intensive therapy. Randomized trials are largely lacking, and the main …
of cases, despite intensive therapy. Randomized trials are largely lacking, and the main …
Integrated stem cell signature and cytomolecular risk determination in pediatric acute myeloid leukemia
… Relapsed or refractory pediatric acute myeloid leukemia (AML) is … for pediatric AML, we
perform RNA-sequencing on 1503 primary diagnostic samples. While a 17 gene leukemia stem …
perform RNA-sequencing on 1503 primary diagnostic samples. While a 17 gene leukemia stem …
Single-cell analysis reveals altered tumor microenvironments of relapse-and remission-associated pediatric acute myeloid leukemia
… Acute myeloid leukemia (AML) microenvironment exhibits … (scRNA-seq) to analyze pediatric
AML bone marrow (BM) samples … Altogether, this study deeply characterizes pediatric AML …
AML bone marrow (BM) samples … Altogether, this study deeply characterizes pediatric AML …
Integrated Genomic Analysis Identifies UBTF Tandem Duplications as a Recurrent Lesion in Pediatric Acute Myeloid Leukemia
… pediatric acute myeloid leukemia (AML) has yet to be comprehensively defined. Here, we
present the spectrum of genomic alterations in 136 relapsed pediatric … de novo pediatric AMLs, …
present the spectrum of genomic alterations in 136 relapsed pediatric … de novo pediatric AMLs, …
Molecular-targeted therapy of pediatric acute myeloid leukemia
P Obszański, A Kozłowska, J Wańcowiat… - Molecules, 2022 - mdpi.com
Acute myeloid leukemia (AML) accounts for approximately 15–20% of all childhood leukemia
cases. The overall survival of children with acute myeloid leukemia does not exceed 82%, …
cases. The overall survival of children with acute myeloid leukemia does not exceed 82%, …
Long noncoding RNA expression independently predicts outcome in pediatric acute myeloid leukemia
… Iterative refinements in risk stratification have been a cornerstone for improved outcomes
in children with leukemia. The criteria used in stratifying pediatric acute myeloid leukemia (…
in children with leukemia. The criteria used in stratifying pediatric acute myeloid leukemia (…
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