Perivascular adipose tissue regulates vascular function by targeting vascular smooth muscle cells

L Chang, MT Garcia-Barrio, YE Chen - … , thrombosis, and vascular …, 2020 - Am Heart Assoc
… on PVAT-mediated VSMC proliferation was further evidenced by studies of visfatin, an adipokine
… of all those growth factors. The significance of PVAT-derived growth factors on vascular

Perivascular adipose tissue and vascular smooth muscle tone: friends or foes?

A Ahmed, A Bibi, M Valoti, F Fusi - Cells, 2023 - mdpi.com
… of endothelial cells, vascular smooth muscle cells (VSMCs), … treatment with the hepatic
fibroblast growth factor 21 (FGF21)… In conclusion, PVAT-derived visfatin may contribute to its pro-…

Role of perivascular adipose tissue-derived adiponectin in vascular homeostasis

A Sowka, P Dobrzyn - Cells, 2021 - mdpi.com
cell dysfunction, recruit proinflammatory immune cells, and induce vascular smooth muscle
cell (VSMC) proliferation. … of angiogenesis is the vascular endothelial growth factor (VEGF). …

Understanding the potential function of perivascular adipose tissue in abdominal aortic aneurysms: current research status and future expectation

XY Liu, T Wen, ZF Wu, NH Deng, HT Liu… - Current medicinal …, 2023 - ingentaconnect.com
… al. delivered adipose tissue-derived mesenchymal stem cells to the … Visfatin was recently
determined to be highly expressed in human macrophages and vascular smooth muscle cells

Potential role of perivascular adipose tissue in modulating atherosclerosis

S Ahmadieh, HW Kim, NL Weintraub - Clinical Science, 2020 - portlandpress.com
… pathways featured vascular endothelial growth factor (VEGF)-… -derived growth factor (PDGF)
and insulin-like growth factor (… augment vascular smooth muscle cell (VSMC) proliferation. …

Perivascular adipose tissue in age-related vascular disease

M Queiroz, CM Sena - Ageing research reviews, 2020 - Elsevier
… adipocytokines, chemokines and growth factors. In an … modulates vascular smooth muscle
cells (VSMCs) tonus, cell … heterogeneous adipose tissue derived from multiple progenitor cells

Role of inflammation in vascular disease-related perivascular adipose tissue dysfunction

Y Chen, Z Qin, Y Wang, X Li, Y Zheng… - Frontiers in …, 2021 - frontiersin.org
… dysfunction involving vascular smooth muscle cells and endothelial cells. … genes) and its
transcription factors may be another … In addition, PVAT secretes free fatty acids, resistin, visfatin, …

Regional heterogeneity of perivascular adipose tissue: morphology, origin, and secretome

X Li, Z Ma, YZ Zhu - Frontiers in Pharmacology, 2021 - frontiersin.org
cell markers, such as platelet-derived growth factor receptor-α (PGDFRα), myogenic factor
5 (Myf5), smooth muscle … fibroblastic progenitor cells but not vascular smooth muscle cells (…

[HTML][HTML] Visfatin as a promising marker of cardiometabolic risk

M Erten - Acta Cardiologica Sinica, 2021 - ncbi.nlm.nih.gov
Vascular smooth muscle proliferation is a specific feature of … Visfatin has been shown to
act as a growth factor for rat … in foam cells as well as smooth muscle cells in atherosclerotic …

The pathobiology of perivascular adipose tissue (PVAT), the fourth layer of the blood vessel wall

C Hillock-Watling, AI Gotlieb - Cardiovascular Pathology, 2022 - Elsevier
… cytokines, chemokines, growth factors (such as VEGF), … II), which acts on vascular smooth
muscle cells in the media to … Resistin and visfatin are two other adipokines that do the …