… 52 to 76 hours after a single dose and 40 to 55 hours after … Importantly, development of
DRM can reduce the virological … mutation, she acquired K101E and K103N mutations with …

… In this study of Kenyan women, virologic failure within 12 … term persistence of HIV-1 variants
with the K103N nevirapine … therapy in women without prior exposure to single-dose NVP…

… mutations detected by Sanger sequencing and revealed … Of the 122 individuals who achieved
virologic suppression after … prevalent NNRTI minority mutations included K103N, Y181C …

… NNRTI mutation, K103N, when detected as a single mutation … minority variants prescribed
EFV-ART had rates of virologic … or exclusion of prior nevirapine (single dose) for prevention of …

… K103N mutation is also the most common mutation to emerge in women who receive single-dose
… presence of resistant viruses existing as a minority to a shorter time in virologic failure. …

… with limited use of single-dose nevirapine (NVP) in isolation), … additional mutations after ART
initiation, with K103N present … to 5% among women who remained virologically suppressed. …

… mutations on the virologic outcome among women taking … We observed that while K103N
in isolation, the most frequent … during gestation and single-dose nevirapine at delivery. After …

… AZT from 28 weeks and a single dose of NVP in labour, while … of these mutations were
mixed codons where the minority … The most common mutations are K103N and Y181C, which …

… The most common mutations (K103N and V108I) were detected in 3/8 pre-ART sequences
(… trial 1, 27 done among women that had prior exposure to single dose nevirapine (sdNVP), …

… /V confers >60-fold resistance to nevirapine and 12- to 15-fold … which twelve female mice
were administered a single dose of … amino acid substitutions (eg, L100I + K103N) in RT (66). In …