Pediatric hiv-1 drug resistance in Botswana

NO Moraka - 2021 - scholar.sun.ac.za
… disease, chronic skin conditions and recurrent diarrhoea. … gestation, then a single dose of
nevirapine (sdNVP) when … ) mutations appear in samples from individuals with virologic failure …

Undisclosed exposure to antiretrovirals prior to treatment initiation: An exploratory analysis

LG Mavhandu-Ramarumo, LAM Tambe… - … African Journal of HIV …, 2021 - ajol.info
… observation of the K103N mutation present in women in the … emerge in women who receive
single-dose nevirapine in the … effect of these DRMs on virological suppression at 6 months, …

A bibliometric analysis of HIV-1 drug-resistant minority variants from 1994 to 2022

C Yan, F Yu, M Li, X Yang, R Sun, X Liang, X Lao… - 2024 - researchsquare.com
… during the process of single-dose nevirapine treatment for preventing mother… women
harboring minority K103N mutations prior to treatment experienced decreased durability in virologic

Clinical Presentation, Treatment Response, and Virology Outcomes of Women Who Seroconverted in the Dapivirine Vaginal Ring Trials—The Ring Study and …

J Steytler, E Van Der Ryst, C Craig… - Clinical Infectious …, 2023 - academic.oup.com
… Indeed, several studies have shown that single-dose nevirapinemutations might affect
response during later exposure to the … -detected mutations, 1 each of minority species K103N (1% …

HIV-1 drug resistance mutations among individuals with low-level viraemia while taking combination ART in Botswana

OT Bareng, S Moyo, M Zahralban-Steele… - Journal of …, 2022 - academic.oup.com
… and virological consequences among individuals on ART. … -associated mutations with
prevalence of >2% were K103N (… fumarate and cabotegravir/nevirapine. Some DRMs may also …

[图书][B] Characterization of HIV-1 Integrase Strand Transfer Inhibitor (INSTI)-Enzyme Interactions Towards Long-Term Strategies to Suppress Viremia, Mitigate …

N Osman - 2020 - search.proquest.com
… a Q148 mutation and one or more accessory mutations (eg … , transmission events persist
within large clusters of … prone reverse-transcription, the highly diverse pool of mutant

Brief Report: Characterizing HIV Drug Resistance in Cases of Vertical Transmission in the VESTED Randomized Antiretroviral Treatment Trial

MD Bishop, V Korutaro, CL Boyce, IA Beck… - JAIDS Journal of …, 2024 - journals.lww.com
… (NNRTI) mutation (K103N) was detected persistently in 1 … amplification to detect HIV minority
frequency variants. … ) has likely reduced virologic failure among women with NNRTI HIVDR. …

HIV-1 genotypic drug resistance testing and Next-generation sequencing

B Liang, M Murray, R Sampathkumar… - Frontiers in Clinical Drug …, 2021 - books.google.com
… For instance, in women who received single-dose nevirapine … were followed by K103N and
M184V during virologic failure [… of virologic failure could even be detected at very low minority

… acquired protease inhibitor drug resistance mutations in minor HIV-1 quasispecies from infected patients suspected of failing on national second-line therapy in South …

AE Obasa, AT Ambikan, S Gupta, U Neogi… - BMC Infectious …, 2021 - Springer
… V82A mutation (n = 13) in protease and K65R (n = 5), K103N … Y181C mutants have a triple
higher risk of virological failure … Several studies have shown that minority pre-treatment drug …

… of treatment-experienced adults after programmatic transitioning to dolutegravir: longitudinal data from the VICONEL human immunodeficiency virus cohort in Lesotho

N Tschumi, M Lerotholi, L Motaboli… - Clinical Infectious …, 2023 - academic.oup.com
… from efavirenz- or nevirapine-based antiretroviral therapy (ART) to … interquartile range (IQR)
for continuous data, and are reported … This study assessed 24-month virologic outcomes and …