… Given that the current study focussed on additional virological … PI-resistant virus strains were
found in a minority of subjects. … are due to the K103N, G190A, and Y181C mutations, which …

… impacts of minority HIV variants on virologic response and … The SVS analysis revealed that
minority variants present at … determination of minority drug-resistance mutations and studies of …

… TDR mutation K103N was found in one (0.7%) patient. Overall, … virological testing to
determine the infection status for HIV-1… prevention study using single-dose nevirapine [140].The …

… infection based the accumulation of mutations in the genome. … are typically not associated
with future virological failure [81]. … exposure to antiretrovirals, including single-dose nevirapine …

… mutations will develop upon ARV drug exposure, and the impact of reduced ARV susceptibility
on virological … (HIV) type 1 M184V and K103N minority variants in patients with primary …

… in virologic suppression or control of chronic conditions could … truncated at 6 months (or a
single dose of study medications) and the … They found that the presence of K103N even at low …

… identifying mutations that contribute to virological failure [74]. … using single dose nevirapine
(NVP), NVP resistance mutations … a single mutation in reverse transcriptase (eg K103N) can …

… testing, and compensatory mutations in Gag may contribute to … In the chronic stage of
infection, the response does expand … testing and detects early virological treatment failure [106]. …

… Early reports from LMICs demonstrated similar virologic and … (a single mutation, most frequently
K103N, is required for high… responses over that achieved by a single dose. The two-dose …

Background Point-of-care (POC) viral load (VL) tests provide results within hours, enabling
same-day treatment interventions. We assessed treatment outcomes with POC vs standard-of-…