Chronic experience with unpredictable food availability promotes food reward, overeating, and weight gain in a novel animal model of food insecurity

KP Myers, M Majewski, D Schaefer, A Tierney - Appetite, 2022 - Elsevier
… to palatable food that habituated in rats with secure HFHS … show that a history of uncertain,
unreliable food access per se … On the other hand, an experimental study of food choice did …

Withdrawal from extended, intermittent access to a highly palatable diet impairs hippocampal memory function and neurogenesis: effects of memantine

A Ferragud, C Velázquez-Sánchez, AA Abdullatif… - Nutrients, 2020 - mdpi.com
… Results: Palatable food withdrawn Chow/Palatable rats … spatial processing and a bias in their
preference for a “novel cue” over … from chronic, intermittent access to a highly palatable diet …

Preference for palatable food, impulsivity, and relation to drug addiction in rats

ME Carroll, NE Zlebnik, NA Holtz - Animal Models of Eating Disorders, 2021 - Springer
… under limited- or short-access conditions, (3) escalation of drug self-administration under …
[92], chronic baclofen treatment was administered over a long-access period in which rats self-…

Intermittent extended access rodent models of compulsive eating

EP Zorrilla, AD Kreisler, SR Bagsic - Animal Models of Eating Disorders, 2021 - Springer
extended diet exposure, because rats that received chronic … by rats over chow in 1-hr,
two-choice taste tests (>99% … have renewed access to palatable food diet at the onset of the rats’ …

Chronic exposure to cafeteria-style diet in rats alters sweet taste preference and reduces motivation for, but not 'liking'of sucrose

J Fam, KJ Clemens, RF Westbrook, MJ Morris… - Appetite, 2022 - Elsevier
… these effects alter the preference for palatable foods and drinks, … In this study access to Caf
diet continued throughout preference … Although lick cluster size was unaffected by diet history, …

The nature of available choices affects the intake and meal patterns of rats offered a palatable cafeteria-style diet

CR Cawthon, AC Spector - Nutrients, 2023 - mdpi.com
continuous recording of changes in weight of up to 5 food … two lick blocks that continuously
record licking to two fluid bottles. … Here, we show that rats find the human-food-based choice

A drug-vs-food choice” self-administration procedure in rats to investigate pharmacological and environmental mechanisms of substance use disorders

EA Townsend, KL Schwienteck, HL Robinson… - Journal of neuroscience …, 2021 - Elsevier
… , extended access drug self-administration or continuous buprenorphine treatment via osmotic
pump) significantly shifted opioid-vs-food choice consistent with previous monkey studies. …

Binge eating, overeating and food addiction: Approaches for examining food overconsumption in laboratory rodents

RM Brown, MH James - Progress in Neuro-Psychopharmacology and …, 2023 - Elsevier
… When measured correctly, food intake and preference provide … limited access compared
to continuous access control rats. … with a history of extended palatable food access (and …

Reward sensitivity deficits in a rat model of compulsive eating behavior

CF Moore, MZ Leonard, NM Micovic… - …, 2020 - nature.com
… a history of alternating standard chow with palatable diet, rats … , Chow/Palatable rats showed
a lower preference for the d-… In contrast to our findings, rats allowed continuous access to a …

Insula to ventral striatal projections mediate compulsive eating produced by intermittent access to palatable food

S Spierling, G De Guglielmo, D Kirson… - …, 2020 - nature.com
… (80–91% mean preference, shown by all rats we have tested [… diet access for rats with
intermittent long access then occurs … Three intermittent shock punishment (FR3), continuous food