More than addiction—The nucleus accumbens contribution to development of mental disorders and neurodegenerative diseases
M Bayassi-Jakowicka, G Lietzau, E Czuba… - International journal of …, 2022 - mdpi.com
… chronic stress and morphological changes to the structure of … and reduction of BDNF levels
in the frontal cortex [77,78] and … a decrease in the amount of DA produced in the VTA. Studies …
in the frontal cortex [77,78] and … a decrease in the amount of DA produced in the VTA. Studies …
… Ventral Tegmental Area (VTA), the Nucleus Accumbens (NAc), the Caudate Nucleus (CN) and the Prefrontal Cortex (PFC) role in the Response to Acute and Chronic …
N King, N Dafny - Journal of Experimental Neurology, 2023 - scientificarchives.com
… , while chronic use of MPD has been reported to produce behavioral … the diverse neuronal
populations in the PFC [11,14] … to the PFC are mixed: with some reporting behavioral changes …
populations in the PFC [11,14] … to the PFC are mixed: with some reporting behavioral changes …
[HTML][HTML] Histone H3 dopaminylation in nucleus accumbens, but not medial prefrontal cortex, contributes to cocaine-seeking following prolonged abstinence
AF Stewart, AE Lepack, SL Fulton, P Safovich… - Molecular and Cellular …, 2023 - Elsevier
… innervation from VTA, with alterations in these inputs in response … within these brain structures
following chronic cocaine exposures… The RNA-seq data generated in this study have been …
following chronic cocaine exposures… The RNA-seq data generated in this study have been …
Opioid-induced structural and functional plasticity of medium-spiny neurons in the nucleus accumbens
… In particular, structural and functional alterations in the … Additionally, glutamatergic neurons
from the prefrontal cortex, … in part, of persistent drug-induced structural and functional synaptic …
from the prefrontal cortex, … in part, of persistent drug-induced structural and functional synaptic …
Dopamine-mediated major depressive disorder in the neural circuit of ventral tegmental area-nucleus accumbens-medial prefrontal cortex: from biological evidence to …
Y Li, B Zhang, X Pan, Y Wang, X Xu… - Frontiers in Cellular …, 2022 - frontiersin.org
… membrane potential changes of dopaminergic neurons in the … persistent sodium channel
of the pyramidal neurons in PFC, … article, or claim that may be made by its manufacturer, is not …
of the pyramidal neurons in PFC, … article, or claim that may be made by its manufacturer, is not …
Neuroplasticity and multilevel system of connections determine the integrative role of nucleus accumbens in the brain reward system
M Bayassi-Jakowicka, G Lietzau, E Czuba… - International Journal of …, 2021 - mdpi.com
… the level of activity of the prefrontal cortex, by modifying the … of changes in myelin structure
in consequence of chronic … reaction generated in NAc is determined by the pattern of neuronal …
in consequence of chronic … reaction generated in NAc is determined by the pattern of neuronal …
Phenylbutyrate ameliorates prefrontal cortex, hippocampus, and nucleus accumbens neural atrophy as well as synaptophysin and GFAP stress in aging mice
FN Carvajal‐Flores, A Díaz, GD Flores‐Gómez… - Synapse, 2020 - Wiley Online Library
… PBA did not modify locomotive activity in a novel environment in the old mice, despite producing
an … Interestingly, our results suggest that the chronic administration of PBA increases the …
an … Interestingly, our results suggest that the chronic administration of PBA increases the …
[HTML][HTML] Transcriptional alterations in dorsolateral prefrontal cortex and nucleus accumbens implicate neuroinflammation and synaptic remodeling in opioid use …
… of molecular alterations due to chronic opioid use and OUD … Focusing on transcript
expression in neurons, we identified … , with the network structure generated on each brain region …
expression in neurons, we identified … , with the network structure generated on each brain region …
Cocaine-induced projection-specific and cell type-specific adaptations in the nucleus accumbens
AK Zinsmaier, Y Dong, YH Huang - Molecular psychiatry, 2022 - nature.com
… -induced adaptive changes in the brain reward circuits. The … from the medial prefrontal cortex,
basolateral amygdala, ventral … which cocaine experience produces persistent synaptic and …
basolateral amygdala, ventral … which cocaine experience produces persistent synaptic and …
Prefrontal Cortical Control of Activity in Nucleus Accumbens Core Is Weakened by High-Fat Diet and Prevented by Co-Treatment with N-Acetylcysteine: Implications …
C Morgan, P Sáez-Briones, R Barra, A Reyes… - International Journal of …, 2022 - mdpi.com
… of HFD can lead to neuroplastic changes an addiction-like … that rats treated with chronic
cocaine displayed significant … and 0.2 Hz in frequency, generated by a Grass S11 stimulator in …
cocaine displayed significant … and 0.2 Hz in frequency, generated by a Grass S11 stimulator in …