… enhancing targeted tissue or organ delivery and reducing … After in vivo administration in
an ischemia mouse model, dual-… the in vitro and in vivo pharmacodynamics by 5.41 and 4.91-…

… and improve delivery of DNA into specific tissues or cell types, … utilize AAV as the gene
delivery platform, this review will … -CB-CFTR, an adenovirus vector containing the cystic fibrosis …

… It was found that the hydrodynamic size distribution and zeta … During the pharmacodynamic
tests, the tumor volumes of … , mouse melanoma cancer B16F10 cell line, and mouse glioma …

… a broad distribution of the vector in the brain tissue and spinal … studied in neonates and adult
mouse models for LSD, as MPS I… It uses a helper-dependent adenovirus vector based on hu…

Adeno-associated viral (AAV) vectors have emerged as the leading gene delivery platform
for gene therapy and vaccination. Three AAV-based gene therapy drugs, Glybera, …

… However, the immune response to the adenovirus vector was a … with deep penetration
into tissues, slightly negative zeta … and unresolved problems in pharmacology. By contrast, …

… For instance, adenovectors possess a rich level of … an AAV-inner ear (AAV-ie) for gene therapy
in a mouse inner ear [298… area, allows controlled delivery at the target tissue, and enables …

… AAV vectors coding for the mouse secretome. In each vector, … , along with the confidence
intervals of each distribution at 95 … and known to modulate inner ear cell proliferation (23), …

… for the delivery of genes in neuromuscular tissues is derived … -body delivery of an
rAAV2/8-Des-mtm1 product in mouse and … lethal systemic inflammation with an adenovirus vector …

… At present, the problems of poor stability and low delivery … died after injecting an adenovirus
vector through the hepatic … and side effects on normal tissues and organs are the current …