A comprehensive review on potential therapeutics interventions for COVID-19

H Chugh, A Awasthi, Y Agarwal, RK Gaur… - … of Pharmacology, 2021 - Elsevier
… difference between the two viruses is distributed throughout the genome randomly instead
of … Recently, a study reported that camostat could block SARS-CoV-2 in a mouse model at a …

Neutrophil Interactions with Sars-CoV-2 and the Development of a Novel Method to Study Immune Cell Dynamics in Mice

M Shevik - 2022 - search.proquest.com
… Preparing the mouse for insertion of the silicone window 79 2.3.3 Inserting a ventral … lung
tissue taken at autopsy has been used to confirm increased neutrophil infiltration into tissues

Targeted Biological and Cellular Immunotherapies for Osteosarcoma

GM Robbins - 2023 - search.proquest.com
… Both allograft and xenograft cell line-derived mouse models … the pharmacokinetic and
pharmacodynamic profiles of drugs… deficient recombinant adenovirus vector and showed a …

mRNA vaccines against infectious diseases and future direction

MT Aleem, F Munir, A Shakoor, F Gao - International Immunopharmacology, 2024 - Elsevier
… This mechanism of mRNA pharmacology makes it beneficial for vaccines and protein
replacement therapies that need transmembrane or cytosolic proteins. The delivery of these …

A genetically encoded actuator selectively boosts l-type calcium channels in diverse physiological settings

PJ del Rivero Morfin, D Scala Chavez, S Jayaraman… - bioRxiv, 2023 - biorxiv.org
… secretion from ribbon synapses in inner ear hair cells that 49 … found that GeeC delivery into
240 mouse hippocampus and … Annual review of 599 pharmacology and toxicology 60, 133-…

Genetic Therapeutic Strategies for Bardet-Biedl Syndrome

MR Cring - 2020 - search.proquest.com
… in mouse models, and the results of my experiments can be used to direct future work aimed
atdelivery methods to introduce a functional copy of a gene to a patient. A more recent …

[PDF][PDF] Novel Drug Delivery Systems Fighting Glaucoma: Formulation Obstacles and Solutions. Pharmaceutics 2021, 13, 28

O Rahic, A Tucak, N Omerovic, M Sirbubalo, L Hindija… - 2020 - pdfs.semanticscholar.org
… The pharmacodynamic study emphasized greater drug BA when dendrimers with …
been proposed for targeted transscleral delivery of therapeutic entities into ocular tissues [262]. …

Current strategies and future perspectives in covid-19 therapy

SR Aravind, KA Mathew, BK Madathil, S Mini… - Stem Cells and COVID …, 2022 - Elsevier
… Finally, the use of biomaterials and tissue engineering approaches for designing
effective interventional strategies is detailed. It is of paramount importance that host-pathogen …

Phenotypic drug screening in a human fibrosis model identified a novel class of antifibrotic therapeutics

M Gerckens, K Schorpp, F Pelizza, M Wögrath… - Science …, 2021 - science.org
… Notably, a substantial number of proteins within this short list are related to tissuemouse
anti-collagen type 5 (1 mg/ml) from Sigma-Aldrich (catalog no. sc-166155), monoclonal mouse

Disease modelling and treatment development for RCBTB1-associated retinopathy

E Huang - 2022 - research-repository.uwa.edu.au
… means gene augmentation therapy based on AAV delivery does not work for all the genes
[… the mouse iPSC-derived retinal tissue/sheets into the fully degenerated retina in mouse and …