[PDF][PDF] Gene therapy with phosphodiesterases 2A and 4B in a murine model of pressure overload-induced cardiac hypertrophy

N Pavlaki - 2021 - ediss.sub.uni-hamburg.de
… , transgenic mouse lines were developed for biosensor expression in adult cardiac tissue/…
By overexpressing PDE2A3 and PDE4B3 in failing mouse hearts, we investigated the β-AR-…

Available compounds with therapeutic potential against COVID-19: antimicrobial therapies, supportive care, and probable vaccines

R Kumar, JK Srivastava, R Singh… - … in pharmacology, 2020 - frontiersin.org
… activity in cell has not been reproduced in the mouse infection models for many viruses. Also,
… One such probable vaccine in the clinical trial stage is the recombinant adenovirus vector

The transmission of SARS-CoV-2 infection on the ocular surface and prevention strategies

K Kitazawa, S Deinhardt-Emmer, T Inomata… - Cells, 2021 - mdpi.com
… protein in the various ocular tissues from patients. However, … experimental or clinical data
in mouse and human models. … In fact, procured and distributed donors have decreased since …

Regulation of VEGF-activated signalling by the plasma membrane calcium ATPase 4 in endothelial cells

RNR Immanuel - 2021 - wlv.openrepository.com
… Armesilla, Cardiovascular Molecular Pharmacology/ Director of … delivery of cytokines using
plasmid vectors or adenovectors … ) mouse models, 4 weeks post vector delivery demonstrating …

Genetic therapeutic strategies for Bardet-Biedl Syndrome

MR Cring - 2020 - search.proquest.com
… in mouse models, and the results of my experiments can be used to direct future work aimed
atdelivery methods to introduce a functional copy of a gene to a patient. A more recent …

[引用][C] Poly (Propylene imine)-based polyplexes for non-viral, targeted delivery of nucleic acids into PSCA-positive tumor cells

W Jugel - 2024 - Dissertation, Dresden, Technische …

[PDF][PDF] PHASE II STUDY OF ADENOVIRUS/PSA VACCINE IN MEN WITH RECURRENT PROSTATE CANCER AFTER LOCAL THERAPY

DM Lubaroff, D Vaena - classic.clinicaltrials.gov
… secreting tumors in a pre-clinical mouse model of prostate cancer (8,… Additional pre-clinical
pharmacology /toxicology studies … intra-tumoral delivery of an adenovirus vector harboring the …

Investigating viral subversion of intercellular communication

PJ Calhoun II - 2020 - vtechworks.lib.vt.edu
… the appropriate distribution of Cx43 gap junctions at intercalated … An adenovirus vector with
genetically modified fibers … human adenoviral vectors in mouse heart tissue which may not …

Current update on severe acute respiratory syndrome coronavirus 2 vaccine development with a special emphasis on gene therapy viral vector design and …

A Bisgin, AD Sanlioglu, YE Eksi, TS Griffith… - Human gene …, 2021 - liebertpub.com
… through genetic modification and delivery methods. Covalent conjugates, … delivery of
mRNA. Furthermore, mRNA vaccines can be administered repeatedly without any concern over

Transdermal material construction in covid 19 vaccine delivery: a microneedle approach

TF Chowdhury - 2021 - dspace.bracu.ac.bd
… infiltrate the ocular tissues which will then quickly dissolve to distribute the drug to both …
response from antigen-specific antibody in a mouse model after 2 weeks of vaccination. The …