… Preterm neonates and those with brain injuries as previously … were lidocaine and midazolam.
Lidocaine infusions were … after the loading dose (either IV or oral). Additional bolus doses …

… Simulations of IV and oral midazolam PK were made in the USPP and a North European
paediatric population (NECP) and compared with the clinical study. The reported trial design …

… Preterm infants (24–29 gestational age) have been reported to present acidic gastric pH, …
Midazolam is an important example of a drug frequently used in dentistry for children with …

… The pervasive belief was that neonates and preterm infants … infants. This hypotension can
result in decreases in oxygen … preterm infants, who were randomized to receive midazolam, …

… of five neonates and midazolam in zero of three neonates. … : 100 mg iv or orally, followed by
30 mg/kg/day iv or orally in … and pharmacodynamic studies for term and preterm neonates; (2…

… Drugs commonly metabolized by this enzyme include midazolam and methadone. Enzyme
activity is substantially reduced in neonates and many of the CYP450 enzymes do not reach …

… metabolism of intravenous midazolam in preterm infants. Clin … Pharmacokinetic and
pharmacodynamic study of midazolam in … and metabolism of oral midazolam in preterm infants. Br …

… transfusions have also been significantly associated with preterm infants with ROP.[ 5 ] Thus,
… [ 8 ] Intravenous, oral, and rectal sedation using different anesthetic agents have also been …

… clearance of fentanyl or midazolam. • Glucuronidation … subsections the relevance of
preterm neonates and critically ill … Morphine is the most commonly used IV opioid in neonates, …

… in preterm and term neonates (p = 0.79 for preterm neonates and p = 0.49 for term neonates).
… So far well-known drugs have been used for these studies in children, such as midazolam …