… in men and women [4]. Importantly, there are also significant differences between men and
women in … In contrast, women benefit more from opioids that interact with the κ-receptor, eg …

… how pharmacokinetics and pharmacodynamics differ based … –receptor interaction which is
called the pharmacodynamic … show differences between men and women because women …

… on the interaction between gender and pharmacogenetics in … Network for Drug Safety, and
additional scientific consortia are … The most striking difference between males and females is …

… of differences in pharmacokinetics and pharmacodynamics, clinically relevant adverse drug
reactions differ between men and women (… suggests that the biology of sex and the impact of …

… scientific community [9]. Regulatory agencies have historically paid insufficient attention to
differences between women and men in … in women and men and considers sex differences in …

… Heterogeneity in study design and biological interactions … biological mechanisms which may
be contributing to the sex … of 50% difference between males and females for at least one PK …

… , transfer between body compartments, biological transformation, and elimination. Many
physiological variations between men and women may account for pharmacokinetic variances, …

… In recent years, rapid breakthroughs in molecular biology … (49), who found no statistically
significant differences between … that our obtained results of pharmacogenomic studies can often …

… , men showed no difference and women showed only a relatively small difference between
… to UGT1A3-mediated drug-drug interactions. Interestingly, nisoldipine has increased the …

… term which biologically identifies males from females in terms … of differences between male
and female pharmacokinetic … Pharmacogenetics has rapidly established itself as a major …