Calcium Regulation of Connexin Hemichannels
E Bayraktar, D Lopez-Pigozzi, M Bortolozzi - International Journal of …, 2024 - mdpi.com
… cascade mediated by the second messenger inositol 1,4,5-… ATP release was not observed
in Cx26 KO or Cx30 KO cultures upon a [Ca2+]c increase triggered by InsP3 photoliberation. …
in Cx26 KO or Cx30 KO cultures upon a [Ca2+]c increase triggered by InsP3 photoliberation. …
Endolysosomal Ca2+ signaling in cardiovascular health and disease
… In addition, EL Ca 2 + release may be triggered by an array of intracellular second …
through the Ca 2 + induced Ca 2 + release (CICR)-dependent recruitment of inositol-1,4,5-…
through the Ca 2 + induced Ca 2 + release (CICR)-dependent recruitment of inositol-1,4,5-…
Correlation between calcium signaling and ATP release mediated by connexin hemichannels in different mouse models of disease
F Mazzarda - 2020 - arcadia.sba.uniroma3.it
… inositol-1,4,5-trisphosphate (IP3), generated intracellularly, and … Summarizing, physiological,
pharmacological and genetic … ATP release is regulated by Ca2+ that triggers the fusion of …
pharmacological and genetic … ATP release is regulated by Ca2+ that triggers the fusion of …
Cx43 channels and signaling via IP3/Ca2+, ATP, and ROS/NO propagate radiation-induced DNA damage to non-irradiated brain microvascular endothelial cells
D Hoorelbeke, E Decrock, M De Smet, M De Bock… - Cell death & …, 2020 - nature.com
… molecules like eg, adenosine triphosphate (ATP), inositol-1,4,5-… a Broad-beam irradiation
triggers ATP release in RBE4 cells. … , some of the pharmacological blockers also had significant …
triggers ATP release in RBE4 cells. … , some of the pharmacological blockers also had significant …
Peptide-based targeting of connexins and pannexins for therapeutic purposes
A Caufriez, D Böck, C Martin, S Ballet… - Expert opinion on drug …, 2020 - Taylor & Francis
… phenylephrine-induced contractile responses and inhibited ATP release in murine … showed
no significant effect on ATP release and other phenylephrine-induced responses. There was …
no significant effect on ATP release and other phenylephrine-induced responses. There was …
Astrocytic connexin43 channels as candidate targets in epilepsy treatment
L Walrave, M Vinken, L Leybaert, I Smolders - Biomolecules, 2020 - mdpi.com
… Given the fact that Cx43 HC ATP release may act as a trigger … Ca 2+ waves induced by
inositol trisphosphate (IP 3 ) in … and promising antiepileptic drug target since selective Cx43 …
inositol trisphosphate (IP 3 ) in … and promising antiepileptic drug target since selective Cx43 …
NMDARs, coincidence detectors of astrocytic and neuronal activities
MW Sherwood, SHR Oliet, A Panatier - International Journal of Molecular …, 2021 - mdpi.com
… Cx43 hemichannels mediate the release of glutamate, ATP, … , the active release of co-agonist
has been triggered by high-… strong stimulation can trigger immediate active release under …
has been triggered by high-… strong stimulation can trigger immediate active release under …
The tissue response to hypoxia: How therapeutic carbon dioxide moves the response toward homeostasis and away from instability
RJ Rivers, CJ Meininger - International journal of molecular sciences, 2023 - mdpi.com
… Elevated tissue CO 2 acts as a sensitive trigger for cellular responses to hypoxia, … connexins
and the release of ATP, which can act on ATP-sensitive potassium (K ATP ) channels in …
and the release of ATP, which can act on ATP-sensitive potassium (K ATP ) channels in …
Role of lipids in interorganelle communication
… Excessive cholesterol in ER membranes triggers release of … Interestingly, genetic or
pharmacological inhibition of the … , and ER, and the photo-liberation of specific fatty acids from the …
pharmacological inhibition of the … , and ER, and the photo-liberation of specific fatty acids from the …
Ca2+ release via InsP3Rs enhances RyR recruitment during Ca2+ transients by increasing dyadic [Ca2+] in cardiomyocytes
K Demydenko, KR Sipido… - Journal of Cell …, 2021 - journals.biologists.com
… detect hormonally induced changes in Ca 2+ release kinetics in … + release in response to
hormonal or pharmacological interventions… Furthermore, photoliberation of InsP 3 from a caged …
hormonal or pharmacological interventions… Furthermore, photoliberation of InsP 3 from a caged …