[HTML][HTML] Gefitinib as neoadjuvant therapy for resectable stage II-IIIA non–small cell lung cancer: A phase II study

Y Zhang, F Fu, H Hu, S Wang, Y Li, H Hu… - The Journal of Thoracic …, 2021 - Elsevier
… Currently, limited data on tyrosine kinase inhibitors as … operable stage II-IIIA NSCLC with
epidermal growth factor receptor … Patients were treated with preoperative gefitinib (250 mg once …

Gefitinib (an EGFR tyrosine kinase inhibitor) plus anlotinib (an multikinase inhibitor) for untreated, EGFR-mutated, advanced non-small cell lung cancer (FL-ALTER) …

HQ Zhou, YX Zhang, G Chen, QT Yu, H Zhang… - … and Targeted Therapy, 2024 - nature.com
… Dual inhibition of vascular endothelial growth factor and epidermal growth factor receptor
(EGFR) … Of note, a recent phase 2 study failed to exhibit the superiority of osimertinib, a third-…

Gefitinib alone versus gefitinib plus chemotherapy for non–small-cell lung cancer with mutated epidermal growth factor receptor: NEJ009 study

…, A Inoue, North-East Japan Study Group - Journal of Clinical …, 2020 - ascopubs.org
growth factor receptor (EGFR) tyrosine kinase inhibitor (TKI) over platinum-based regimens
… a randomized phase II study, NEJ005, that compared the concurrent use of gefitinib and …

Is there a role for dacomitinib, a second-generation irreversible inhibitor of the epidermal-growth factor receptor tyrosine kinase, in advanced non-small cell lung …

C Bergonzini, A Leonetti, M Tiseo… - Expert opinion on …, 2020 - Taylor & Francis
… a large family of EGFR tyrosine kinase inhibitors (TKI) were … in a phase III randomized study
compared with gefitinib, a first-… In the ARCHER 1042 [Citation29] phase II trial, the effect on …

[HTML][HTML] Apatinib plus gefitinib as first-line treatment in advanced EGFR-mutant NSCLC: the phase III ACTIVE study (CTONG1706)

H Zhao, W Yao, X Min, K Gu, G Yu, Z Zhang… - Journal of thoracic …, 2021 - Elsevier
… vascular endothelial growth factor receptor 2 tyrosine kinase inhibitor, plus … Epidermal growth
factor receptor … placebo-controlled phase 2 study 26 on advanced NSCLC after two lines of …

Nationwide real-world cohort study of first-line tyrosine kinase inhibitor treatment in epidermal growth factor receptor-mutated non–small-cell lung cancer

RGP Gijtenbeek, RAM Damhuis, HJM Groen… - Clinical lung cancer, 2020 - Elsevier
… A meta-analysis that summarized direct analysis between gefitinib and erlotinib showed no
… (6 studies; 303 patients) did not differ between treatments with erlotinib or gefitinib, as these …

Adjuvant treatment with tyrosine kinase inhibitors in epidermal growth factor receptor mutated non-small-cell lung carcinoma patients, past, present and future

W Shalata, BM Jacob, A Agbarya - Cancers, 2021 - mdpi.com
… /without Gefitinib Trial In this phase II study, 60 patients with resected NSCLC bearing EGFR
mutations, exon 19 deletion or L858R, were enrolled [29]. Participants with stage IIIA were …

[HTML][HTML] Fruquintinib with gefitinib as first-line therapy in patients carrying EGFR mutations with advanced non-small cell lung cancer: a single-arm, phase II study

S Lu, JY Zhou, XM Niu, JY Zhou, H Jian… - Translational Lung …, 2021 - ncbi.nlm.nih.gov
stage IIIB/IV NSCLC and an epidermal growth factor receptor (… tyrosine kinase inhibitors
(TKIs) are the standard initial treatment for patients with EGFR mutation-positive NSCLC; gefitinib

Overall survival in advanced epidermal growth factor receptor mutated non-small cell lung cancer using different tyrosine kinase inhibitors in The Netherlands: a …

RGP Gijtenbeek, RAM Damhuis… - The Lancet Regional …, 2023 - thelancet.com
… to the first-generation TKI erlotinib or gefitinib in the FLAURA study. In a post hoc analysis,
a … A randomised phase II study of osimertinib and bevacizumab versus osimertinib alone as …

A Phase 1 study of gefitinib combined with durvalumab in EGFR TKI-naive patients with EGFR mutation-positive locally advanced/metastatic non-small-cell lung …

BC Creelan, TC Yeh, SW Kim, N Nogami… - British journal of …, 2021 - nature.com
… EGFR tyrosine kinase inhibitors (TKIs) induce cytolysis and … Epidermal growth factor receptor
(EGFR) tyrosine kinase … resistance, 30 a recent Phase 2 study found that pembrolizumab …