Phenotypic CD8 T cell profiling in chronic hepatitis B to predict HBV-specific CD8 T cell susceptibility to functional restoration in vitro

…, G Missale, P Lampertico, C Ferrari, C Boni - Gut, 2023 - gut.bmj.com
hepatitis B virus (HBV)-specific CD8 T cells in chronic HBV infection are broadly heterogeneous.
Characterisation of their functional … Ex vivo HBV-specific T cell functional analysis. …

Tissue-resident memory T cells in chronic liver diseases: Phenotype, development and function

Y Li, Z You, R Tang, X Ma - Frontiers in Immunology, 2022 - frontiersin.org
chronic liver diseases. Here, we provide insights into the phenotype of hepatic T RM cells
through … Hepatoviral infection is mainly caused by the hepatitis B (HBV) and hepatitis C (HCV) …

Lymphocyte Landscape after Chronic Hepatitis C Virus (HCV) Cure: The New Normal

A Ghosh, S Romani, S Kottilil, B Poonia - International Journal of …, 2020 - mdpi.com
… subset that comprise between 5 and 10% of peripheral T cells and about 12–50% of T cells
… of virus-specific T cells towards memory or exhaustive phenotype; these signatures involved …

Longitudinal characterization of phenotypic profile of T cells in chronic hepatitis B identifies immune markers predicting HBsAg loss

S Xiong, D Zhu, B Liang, M Li, W Pan, J He, H Wang… - bioRxiv, 2020 - biorxiv.org
… a longitudinal analysis of the T cell phenotype and function during … , T cell phenotype profiles
and HBV-specific T cell responses … prior to, during and after achieving functional cure upon …

[PDF][PDF] Phenotypic, functional characterisation and transcriptomic analysis of CD8+ T memory stem cell and its role in HCV re-infection

Y Zhao - 2021 - unsworks.unsw.edu.au
… of antigen-specific CD8 TSCM during hepatitis Cwhile the phenotype and/or function of
numerically stable circulatory memory CD8 T cells are defined by the age of memory CD8 T cell (…

Phenotype and fate of liver-resident CD8 T cells during acute and chronic hepacivirus infection

P Dravid, S Murthy, Z Attia, C Cassady… - PLoS …, 2023 - journals.plos.org
… Broadly directed virus-specific CD4+ T cell responses are primed during acute hepatitis
C infection, but rapidly disappear from human blood with viral persistence. The Journal of …

[HTML][HTML] Multi-parametric analysis of human livers reveals variation in intrahepatic inflammation across phases of chronic hepatitis B infection

…, A Aggarwal, N van Buuren, M Doukas, C Moon… - Journal of …, 2022 - Elsevier
phenotype of circulating natural killer (NK) cells, T cells and B-… of T cells in livers at chronic
HBV phases which were further increased in phases with elevated ALT (IA and ENEG) when

Chronic Hepatitis C Virus Infection Modulates the Transcriptional Profiles of CD4+ T Cells

M Holub, A Stráníková, O Beran… - Canadian Journal of …, 2021 - Wiley Online Library
… First, we did not evaluate the phenotypes of circulating CD4 + T cells using analysis of
intracellular cytokines. Nevertheless, our findings are consistent with previous studies. Second, …

Imprint of unconventional Tcell response in acute hepatitis C persists despite successful early antiviral treatment

Y Du, T Khera, B Strunz, K Deterding… - European Journal of …, 2022 - Wiley Online Library
Phenotypic characteristics of unconventional T cells in patients with acute and chronic
HCV infection. (A) Summary of data for the expression of Ki-67, CD69, CD38, HLA-DR, PD-1, …

… cruzi antigens, activated peripheral T lymphocytes retained in the liver induce a proinflammatory phenotypic and functional shift in intrahepatic T lymphocyte

M Meuser-Batista, N Vacani-Martins… - Journal of Leukocyte …, 2020 - academic.oup.com
analysis, there was an increase in the number of effector/T em cells in the T cell and T cell+…
After the adoptive transfer of activated peripheral T cells, we found an increase of at least 2.5…