[HTML][HTML] Peripheral blood iNKT cell activation correlates with liver damage during acute hepatitis C

T Senff, C Menne, C Cosmovici, LL Lewis-Ximenez… - JCI insight, 2022 - ncbi.nlm.nih.gov
… Because it has been shown that an activated phenotype is a common feature of intrahepatic
T cells and not only a hallmark of HCV-specific T cells, we next determined the general …

Single-cell heterogeneity of the liver-infiltrating lymphocytes in individuals with chronic echinococcus multilocularis infection

…, T Aji, Y Shao, C Guo, C Zhang, B Ran… - Infection and …, 2022 - Am Soc Microbiol
… To reveal the potential functional subtypes of CD8 + T cells, we performed a comparison …
Patients with hepatitis B virus (HBV), hepatitis C virus (HCV), or human immunodeficiency virus (…

[HTML][HTML] Immunomodulation of the natural killer cell phenotype and response during HCV infection

GF Njiomegnie, SA Read, N Fewings, J George… - Journal of clinical …, 2020 - mdpi.com
… The antiviral immune response to hepatitis C is traditionally understood to be driven by
the adaptive immune cells such as B cells and T cells, and more recently by innate immune …

[HTML][HTML] Reconstitution of T follicular helper-humoral immune axis with elimination of hepatitis C virus

A Khanam, S Kottilil, E Wilson - Scientific Reports, 2020 - nature.com
… of phenotypic and functional abnormalities of T FH -B cell axis. … in B cell compartment have
been reported during chronicB cells do not alter, but the prevalence of activated B cells has …

[HTML][HTML] Peripheral immune characteristics of hepatitis B virus-related hepatocellular carcinoma

R Sun, J Li, X Lin, Y Yang, B Liu, T Lan, S Xiao… - Frontiers in …, 2023 - frontiersin.org
phenotype of various immune cells in the periphery of HBV-… of PB T cells, B cells, NK cells,
NKT cells, γδ T cells. We found … + T cells in peripheral blood lymphocytes of patients with HBV-…

[HTML][HTML] Hepatic ILC2 activity is regulated by liver inflammation-induced cytokines and effector CD4+ T cells

S Steinmann, M Schoedsack, F Heinrich, PC Breda… - Scientific reports, 2020 - nature.com
… In the present study, we investigated the phenotype and plasticity of hepatic ILC2 in
response to liver inflammation-induced cytokines and effector CD4 + T cells in order to identify …

[HTML][HTML] Macrophage phenotype and function in liver disorder

L Dou, X Shi, X He, Y Gao - Frontiers in immunology, 2020 - frontiersin.org
… (A) Hepatic macrophages and hepatitis B virus (HBV)/hepatitis C virus (HCV). Interleukin (IL)…
recruit natural killer cells, natural killer T cells, dendritic cells, and CD4+ T cells to infected …

Epigenetic scars in regulatory T cells are retained after successful treatment of chronic hepatitis C with direct-acting antivirals

SY Kim, JY Koh, DH Lee, HD Kim, SJ Choi, YY Ko… - Journal of …, 2024 - Elsevier
… Nevertheless, we have demonstrated that inflammatory features of T REG cells are maintained
at phenotypic, transcriptomic, and epigenetic levels even after successful DAA treatment. …

[HTML][HTML] Distinct histopathological phenotypes of severe alcoholic hepatitis suggest different mechanisms driving liver injury and failure

J Ma, A Guillot, Z Yang, B Mackowiak… - The Journal of …, 2022 - Am Soc Clin Investig
… model of chronic-plus-binge alcohol feeding, known to be associated with high intrahepatic
… analyses an increase in intrahepatic neutrophils with minimal CD8 + T cell infiltration in the …

[HTML][HTML] Cirrhosis hampers early and rapid normalization of natural killer cell phenotype and function in hepatitis C patients undergoing interferon-free therapy

…, MC Londoño, Z Mariño, C Bartres… - Frontiers in …, 2020 - frontiersin.org
… Our study focused on the phenotypic and functional analysis of peripheral NK cells, … cells
imprinted in a liver-specific manner. These intrahepatic NK cells contain liver resident NK cells