The T cell receptor immune repertoire protects the liver from reconsitution

Q Liang, Y Hu, M Zhang, C Lin, W Zhang, Y Li… - Frontiers in …, 2020 - frontiersin.org
… stellate cells (HSCs) induced by the upregulation of macrophage and γδ T cell distribution in
… Our findings reveal the landscape and dynamics of single immune cells in liver fibrosis, and …

Effector memory CD8 T cell response elicits Hepatitis E Virus genotype 3 pathogenesis in the elderly

H El Costa, J Gouilly, F Abravanel, E Bahraoui… - PLoS …, 2021 - journals.plos.org
… To assess whether HEV-3 infection shapes the phenotype of CD8 T cells, we analyzed the
expression of subset markers (CCR7 and CD45RA), activation markers (HLA-DR and CD38), …

Reversal of T cell exhaustion in chronic HCV infection

S Osuch, KJ Metzner, K Caraballo Cortés - Viruses, 2020 - mdpi.com
… On a phenotypic level, T cell exhaustion during chronic infection is manifested as … Until
recently, the standard of care for chronic hepatitis C was a combination of pegylated-IFN-α (PEG-…

Activated CD8 T-cell hepatitis in children with indeterminate acute liver failure: results from a multicenter cohort

…, H Melin-Aldana, PA Kreiger, T Burn… - Journal of pediatric …, 2020 - journals.lww.com
… , consistent with an effector memory phenotype. We propose that CD8 T cells are a biomarker
of the IND-PALF “activated CD8 T-cell hepatitisphenotype and may be used to identify …

Clinical features and T cell immune characteristics of postpartum hepatitis flare in pregnant women with HBeAg-positive chronic HBV infection

A Song, Y Liu, Z Cao, J Lu, S Ren, S Zheng… - Frontiers in …, 2022 - frontiersin.org
… patients with infections of hepatitis A, hepatitis C, human … T cells and phenotypic subsets.
Expression of CD38 and HLA-DR on CD8 + T cells (A), TEM subsets (B) and TEMRA subsets (C

Gamma-Chain Receptor Cytokines & PD-1 Manipulation to Restore HCV-Specific CD8+ T Cell Response during Chronic Hepatitis C

J Peña-Asensio, H Calvo, M Torralba, J Miquel… - Cells, 2021 - mdpi.com
… specific CD8 T cell reactivity, as it will be discussed later [32]. … in increasing functionality of
HCV-specific cytotoxic T cells, … exhausted T cells, which will transfer the exhausted phenotype

Phenotypic changes of PD-1 and GITR in T cells are associated with hepatitis b surface antigen seroclearance

F Liu, S Zhang, DKH Wong, FY Huang… - Journal of Clinical …, 2022 - journals.lww.com
… Patients with following conditions were excluded: concomitant chronic hepatitis C or D
infection, primary sclerosing cholangitis, primary biliary cholangitis, autoimmune …

Priming of antiviral CD8 T cells without effector function by a persistently replicating hepatitis C-like virus

AS Hartlage, CM Walker, A Kapoor - Journal of virology, 2020 - Am Soc Microbiol
… and gain insights into the nature of their impairment, we performed a detailed analysis of
their phenotype during infection. Using the class I tetramers described above, we monitored for …

Innate-like T lymphocytes in chronic liver disease

M Papanastasatou, M Verykokakis - Frontiers in Immunology, 2023 - frontiersin.org
… 3.1 Hepatitis B virus and hepatitis C virus Hepatitis B and hepatitis C viruses are the most …
Peripheral MAIT cells are characterized by an exhausted phenotype, as shown by the …

A subset of liver resident natural killer cells is expanded in hepatitis C-infected patients with better liver function

…, B Haydel, SS Florman, MI Fiel, T Schiano… - Scientific Reports, 2021 - nature.com
… to phenotype immune cells associated with preservation of normal liver function during
hepatitis C … but are resistant to ConA T cell-mediated hepatitis. After partial hepatectomy, liver …