Gamma-Delta T-cell phenotype and function in DAA-Treated HIV-HCV Co-Infected and HCV-mono-infected subjects

V Bono, C Tincati, L Van Den Bogaart, ES Cannizzo… - Viruses, 2022 - mdpi.com
… on immune cell populations playing a role in fibrogenesis is unknown. We assessed γδ T-cell
phenotype and function, Treg and Th17 frequencies, as well as γ-globulins and B-cell

[HTML][HTML] Diverse functions of γδ T cells in the progression of hepatitis B virus and hepatitis C virus infection

W Hou, X Wu - Frontiers in Immunology, 2021 - frontiersin.org
… Although human peripheral Vγ9Vδ2 T cells display an elevated effector phenotype in
sustained virologic-response HCV patients, recent DAA treatment research demonstrates that …

Characterization of intrahepatic B cells in acute-on-chronic liver failure

Y Zhao, W He, C Wang, N Cui, C Yang, Z You… - Frontiers in …, 2022 - frontiersin.org
… A variety of immune cells including NK, CD4 + T cells, CD8 + T cells, … intrahepatic B cells
in ACLF and found that these B-cell subpopulations were phenotypically and functionally

Innate‐like bystander‐activated CD38+ HLA‐DR+ CD8+ T cells play a pathogenic role in patients with chronic hepatitis C

CH Huang, JH Fan, WJ Jeng, ST Chang, CK Yang… - Hepatology, 2022 - journals.lww.com
… CD8 + T cells function mainly as memory T cells and express … ‐DR − CD8 + T cells among
those with chronic HCV infection, … of the phenotype between CD38 + HLA‐DR + CD8 + T cells

T-cell exhaustion and residency dynamics inform clinical outcomes in hepatocellular carcinoma

…, C Tauber, P Otto-Mora, T Ohtani, T Nilsson… - Journal of …, 2022 - Elsevier
… , metabolic and functional status of these cell populations. The … CD8 T cells are associated
with an exhaustion phenotype … , chronic hepatitis B virus infection; cHCV, chronic hepatitis C

[HTML][HTML] Chronic hepatitis C pathogenesis: immune response in the liver microenvironment and peripheral compartment

…, MS Caldirola, MI Gaillard, C Giadans… - Frontiers in Cellular …, 2021 - frontiersin.org
… , differentiation, and functional status on PB were evaluated by … On one hand, cytotoxic T
lymphocytes (CTL, CD8+ T cells) … lymphocytes and an increase in EM phenotype and activated …

… of Trypanosoma cruzi antigens, activated peripheral T lymphocytes retained in the liver induce a proinflammatory phenotypic and functional shift in intrahepatic T …

M Meuser-Batista, N Vacani-Martins… - Journal of Leukocyte …, 2020 - academic.oup.com
… and activated T cells in altering the phenotype and function of intrahepatic T lymphocytes, …
T cells and the hepatic inflammatory response. To date, Bowen elegantly showed that when …

Single-cell atlas reveals characteristic changes in intrahepatic HBV-specific leukocytes

B Pan, Z Wang, R Chen, X Zhang, J Qiu… - Microbiology …, 2024 - Am Soc Microbiol
… weak HBV-specific T cell responses We analyzed the phenotype of intrahepatic T cells in
more … Multiple factors such as leukocyte subsets, number, spatial location, functional status, …

Immunological monitoring in hepatitis C virus controlled human infection model

NH Shoukry, AL Cox, CM Walker - Clinical Infectious Diseases, 2023 - academic.oup.com
T cells in the liver may also exhibit phenotypic and functional … + T cells are required for
protection from persistent hepatitis CIntrahepatic CD8+ T-cell failure during chronic hepatitis C

[HTML][HTML] Intrahepatic CD69+ Vδ1 T cells re-circulate in the blood of patients with metastatic colorectal cancer and limit tumor progression

…, P Kunderfranco, C Peano, C Soldani… - … for Immunotherapy of …, 2022 - ncbi.nlm.nih.gov
… in PB and tumor mass (figure 6C, D), we proceeded to assess the frequencies, phenotypes
and TCR repertoires of circulating Vδ1 T cells in patients with CLM. Multiparametric flow …