[HTML][HTML] Intrahepatic CD69+ Vδ1 T cells re-circulate in the blood of patients with metastatic colorectal cancer and limit tumor progression

…, P Kunderfranco, C Peano, C Soldani… - … for Immunotherapy of …, 2022 - ncbi.nlm.nih.gov
… in PB and tumor mass (figure 6C, D), we proceeded to assess the frequencies, phenotypes
and TCR repertoires of circulating Vδ1 T cells in patients with CLM. Multiparametric flow …

[HTML][HTML] T cell immunity to hepatitis C virus: Lessons for a prophylactic vaccine

R Thimme - Journal of hepatology, 2021 - Elsevier
… Viral escape also leaves an imprint on the phenotype of virus-specific CD8+ T cells. Indeed,
… expansion of peripheral and intrahepatic HCV-specific CD8+ T cell responses that cross-…

[PDF][PDF] Double Positive CD4+CD8+(DP) T-Cells Display Distinct Exhaustion Phenotype in Chronic Hepatitis C. Cells 2023, 12, 1446

AM Kochanowicz, S Osuch, H Berak, A Kumorek… - 2023 - ppm.wum.edu.pl
T cell immunity to hepatitis C virus: Lessons for a prophylactic vaccine. J. Hepatol. … on
circulating and intrahepatic hepatitis C virus-specific CD8+ T cells associated with reversible …

Lymphocyte Landscape after Chronic Hepatitis C Virus (HCV) Cure: The New Normal

A Ghosh, S Romani, S Kottilil, B Poonia - International Journal of …, 2020 - mdpi.com
… 10% of peripheral T cells and about 12–50% of T cells in the … persisting dysfunctional
phenotype and functional state in a … A skewing of intrahepatic T cells towards a higher Th17/FoxP3 …

Mucosal‐associated invariant Tcells are severely reduced and exhausted in humans with chronic HBV infection

W Huang, W He, X Shi, Q Ye, X He… - … of viral hepatitis, 2020 - Wiley Online Library
… found that MAIT cells in patients with chronic hepatitis C virus … , we hypothesized that
intrahepatic MAIT cells may have a … the phenotypes and activation status of MAIT cells in the liver …

Tcell mediated responses against alpha‐foetoprotein in hepatocellular carcinoma: Relationship with hepatitis C virus infection, tumour phenotype and patients' …

…, G Occhino, E Boccato, C Smirne… - Liver Cancer …, 2021 - Wiley Online Library
… + lymphocytes. Although we did not fully dissect the phenotype of the IL-2-secreting T cell
and colleagues, where anti-AFP CD8+ cells were isolated from a smaller group of eight …

[PDF][PDF] Analysis of invariant natural killer T cells in health and disease: lessons from acute hepatitis C virus infection

C Menne - 2022 - docserv.uni-duesseldorf.de
… NKT cells are unconventional T cells that phenotypically and functionally resemble both
NK cells and T cells. Even though they possess many characteristics from the innate immune …

Enolase represents a metabolic checkpoint controlling the differential exhaustion programmes of hepatitis virus-specific CD8+ T cells

…, L Hannibal, C Neumann-Haefelin, T Boettler… - Gut, 2023 - gut.bmj.com
… murine intrahepatic HBV-specific CD8 + T cells in chronic but … cHBV, chronic hepatitis B
virus; cHCV, chronic hepatitis CT cell phenotype with the clinical activity in chronic HBV and …

[HTML][HTML] Long-Lasting Virus-Specific T Cell Response with Divergent Features in Self-Resolved and Chronic Hepatitis C Virus Patients 35 Years Postinfection

W Ji, M Zhao, J Zhou, H Zheng, N Li, B Han, W Yin… - …, 2022 - journals.aai.org
… This failure of intrahepatic virus-specific CD8 + T cells to sufficiently control the virus
occurs … To investigate the memory phenotype of T cells, we analyzed PBMCs based on the …

Immunological mechanisms for hepatocellular carcinoma risk after direct-acting antiviral treatment of hepatitis C virus infection

PS Sung, EC Shin - Journal of clinical medicine, 2021 - mdpi.com
… player of intrahepatic innate and adaptive immunity: hepatocytes, NK … T-cell function [73].
This provides support to the theory that the exhausted phenotype of HCV-specific CD8 + T cells