Mouse primary microglia respond differently to LPS and poly (I: C) in vitro
Y He, N Taylor, X Yao, A Bhattacharya - Scientific Reports, 2021 - nature.com
… phenotypes. In this study, we compared the phenotypes in microglia in response to LPS and
… could impair migration towards ATP in primary rat 41 and human microglia 42 , which was …
… could impair migration towards ATP in primary rat 41 and human microglia 42 , which was …
The human microglia responsome: a resource to better understand microglia states in health and disease
G Snijders, K de Paiva Lopes, M Sneeboer, B Muller… - bioRxiv, 2023 - biorxiv.org
… of human microglia to the response of human monocytes, a … By comparing our human
microglia LPS signatures to mice, … genes after skewing human microglia phenotypes in vitro are …
microglia LPS signatures to mice, … genes after skewing human microglia phenotypes in vitro are …
Mapping the plasticity of morphology, molecular properties and function in mouse primary microglia
X Jiang, H He, L Mo, Q Liu, F Yang, Y Zhou… - Frontiers in Cellular …, 2022 - frontiersin.org
… phenotypes in mouse primary microglia. RNA sequencing was used to identify genes
differentially expressed in response … factor-beta differentially regulate lipopolysaccharide-induced …
differentially expressed in response … factor-beta differentially regulate lipopolysaccharide-induced …
Microglia phenotypes in aging and neurodegenerative diseases
MY Wendimu, SB Hooks - Cells, 2022 - mdpi.com
… protective phenotypes, and the overall response of microglia … human microglia, as there is
shortage of postmortem human … transform into an amoeboid phenotype by LPS treatment [38,…
shortage of postmortem human … transform into an amoeboid phenotype by LPS treatment [38,…
[HTML][HTML] Microglial heterogeneity: distinct cell types or differential functional adaptation?
… microglial phenotypes from three commonly used central nervous system inflammation
murine models to study microglial response … LPS mediates a peripheral immune response that …
murine models to study microglial response … LPS mediates a peripheral immune response that …
Organotypic brain slice culture microglia exhibit molecular similarity to acutely-isolated adult microglia and provide a platform to study neuroinflammation
ARD Delbridge, D Huh, M Brickelmaier… - Frontiers in Cellular …, 2020 - frontiersin.org
… the changes in microglia phenotype that occur over time in … possibly triggering a microglia
inflammatory response early in the … of the in vivo microglia transcriptional response to LPS was …
inflammatory response early in the … of the in vivo microglia transcriptional response to LPS was …
Serial systemic injections of endotoxin (LPS) elicit neuroprotective spinal cord microglia through IL-1-dependent cross talk with endothelial cells
… that a neuroprotective spinal cord microglia response can be … LPS elicits a protective or
destructive microglia phenotype is … a narrow beam without falling (vehicle-LPS, n = 6; PLX-LPS, n …
destructive microglia phenotype is … a narrow beam without falling (vehicle-LPS, n = 6; PLX-LPS, n …
Endocannabinoid modulation of microglial phenotypes in neuropathology
M Tanaka, S Sackett, Y Zhang - Frontiers in Neurology, 2020 - frontiersin.org
… data for the immune response and phenotype characterization … When mouse primary microglia
activated by LPS and IFNγ … is tightly regulated by the M2 polarization sub-phenotype, and, …
activated by LPS and IFNγ … is tightly regulated by the M2 polarization sub-phenotype, and, …
Modulatory effect of IL‐1 inhibition following lipopolysaccharide‐induced neuroinflammation in neonatal microglia and astrocytes
WC Pierre, I Londono, C Quiniou… - International Journal …, 2022 - Wiley Online Library
… phenotypes of combined glial cells (astrocytes and microglia… iNOS expression is tightly
regulated by nuclear factor-kappa … the LPS-induced inflammatory response in microglia and …
regulated by nuclear factor-kappa … the LPS-induced inflammatory response in microglia and …
Dynamic interleukin-1 receptor type 1 signaling mediates microglia-vasculature interactions following repeated systemic LPS
… Following 4d LPS, we found multiple phenotypes that are … cellular response to 4d LPS,
requiring endothelial and microglial … associated with tight junction gene expression in microglia. In …
requiring endothelial and microglial … associated with tight junction gene expression in microglia. In …