… To determine if TbSpl expression is essential for survival of T. brucei, growth of TbSpl KO …
, a sub-compartment of ER and mitochondria commonly known as mitochondria associated …

… , the synthesis of cardiolipin is essential for growth of … CL associates with several respiratory
chain complexes and … is used by phosphatidylglycerophosphate (PGP) synthase to produce …

… should rescue the defect in PE synthesis and restore growth of T. …
Phosphatidylglycerophosphate synthase associates with a mitochondrial inner membrane complex …

… glycerophospholipid that associates with mitochondrial … acid, CDP-diacylglycerol,
phosphatidylglycerophosphate and … 0.05) in several key metabolites associated with energy …

… machinery required for both PI and CL synthesis identifying a key … is associated to the matrix
side of the inner mitochondrial … Trypanosoma brucei, the causative agent of African sleeping …

… protein Gpi2, which is essential for the activity of the complex in yeast and mammals, but the
… , we exploited Trypanosoma brucei (Tb), an early diverging eukaryote and important model …

… The dermis as a delivery site of trypanosoma brucei for tsetse flies. Plos Pathogens 12(7):…
Trypanosoma brucei parasites occupy and functionally adapt to the adipose tissue in mice. …

… pathway is essential for survival of Trypanosoma brucei procyclic … and phosphatidylcholine
for membrane biogenesis. The CDP-… Although TbFAAH is not essential for growth of T. …

… gene encoding the Trypanosoma brucei homolog TbSlp2 has … phosphatidylglycerophosphate
synthase (PGS1) and cardiolipin … To study if TbSlp2-HA is membrane-associated, we used …

… protein [6,7], is unique and essential to BSF trypanosomes; … brucei mitochondrion will affect
the mitochondrial membrane … from the extra fluorescence associated with any changes in …