[HTML][HTML] Phospholipid turnover and acyl chain remodeling in the yeast ER

J Patton-Vogt, AIPM de Kroon - … et Biophysica Acta (BBA)-Molecular and …, 2020 - Elsevier
phospholipid constituents found in the yeast ER membrane [11], and the enzymes involved.
Since PC is at the end of the phospholipid biosynthetic … serve as biosynthetic intermediates …

Rewiring phospholipid biosynthesis reveals resilience to membrane perturbations and uncovers regulators of lipid homeostasis

AT John Peter, SNS van Schie, NJ Cheung… - The EMBO …, 2022 - embopress.org
… Here, we present an approach in which we simplify and rewire yeast phospholipid synthesis
by redirecting PE and PC synthesis reactions to distinct subcellular locations using chimeric …

Engineering yeast phospholipid metabolism for de novo oleoylethanolamide production

Y Liu, Q Liu, A Krivoruchko, S Khoomrung… - Nature Chemical …, 2020 - nature.com
… Here, we present the development of a metabolically engineered yeast strain … of a yeast
phospholipid platform strain, which then serves as the host for reconstructing OEA biosynthesis. …

[HTML][HTML] Yeast phosphatidic acid phosphatase Pah1 hops and scoots along the membrane phospholipid bilayer

JM Kwiatek, GM Carman - Journal of lipid research, 2020 - ASBMB
… synthesis and in the regulation of phospholipid synthesis. As an … yeast PA phosphatase.
This system, however, does not resemble the in vivo environment of the membrane phospholipid

Yeast Rim11 kinase responds to glutathione-induced stress by regulating the transcription of phospholipid biosynthetic genes

T Yasukawa, R Iwama, Y Yamasaki… - Molecular Biology of …, 2024 - Am Soc Cell Biol
yeast that restores growth under GSH stress. Rim11 plays important roles in the regulation of
phospholipid biosynthesis … to efficient breeding of yeast strains with enhanced production of …

Phospholipid biosynthesis disruption renders the yeast cells sensitive to antifungals

D Kundu, S Hameed, Z Fatima, R Pasrija - Folia Microbiologica, 2020 - Springer
… Thus, this study proposes phospholipid biosynthesis as a … turned the yeast cell sensitive, and
phospholipids biosynthesis can … Interestingly, many enzymes in phospholipids biosynthesis

[HTML][HTML] Phosphatidic acid mediates the Nem1-Spo7/Pah1 phosphatase cascade in yeast lipid synthesis

JM Kwiatek, B Gutierrez, EC Izgu, GS Han… - Journal of lipid …, 2022 - ASBMB
… into phospholipid vesicles prepared in accordance with the phospholipid composition of the
… was located at the external side of the phospholipid bilayer. Moreover, we determined that …

[HTML][HTML] Phosphatidic acid biosynthesis in the model organism yeast Saccharomyces cerevisiae-a survey

K Athenstaedt - Biochimica et Biophysica Acta (BBA)-Molecular and …, 2021 - Elsevier
… In addition, yeast and mammals harbor a set of enzymes which can synthesize phosphatidic
… to phosphatidic acid biosynthesis in the invaluable model organism yeast, Saccharomyces …

[HTML][HTML] Ino2, activator of yeast phospholipid biosynthetic genes, interacts with basal transcription factors TFIIA and Bdf1

M Engelhardt, S Hintze, EC Wendegatz, J Lettow… - Current Genetics, 2023 - Springer
… We have previously shown that the yeast transcriptional activator Ino2 of phospholipid
biosynthetic genes is able to interact with two separate subdomains of Taf1 (aa 1–100 = ABD1, …

Metabolism of phospholipids in the yeast Schizosaccharomyces pombe

R Holič, L Pokorná, P Griač - Yeast, 2020 - Wiley Online Library
… we describe the biosynthetic pathways leading to major S. pombe phospholipids, how these
… about degradation and turnover of fission yeast phospholipids. This review also addresses …