[HTML][HTML] Melanin, lipofuscin and the effects of visible light in the skin

PN Tonolli, MS Baptista, O Chiarelli-Neto - Journal of Photochemistry and …, 2021 - Elsevier
… into l-DOPA and other oxidation products, which are reactive among themselves, favoring
self-polymerization and production of two main types of melanin: eumelanin and pheomelanin. …

The effect of oxidative degradation of Dopa‐melanin on its basic physicochemical properties and photoreactivity

K Mokrzyński, A Żądło, G Szewczyk… - Pigment Cell & …, 2024 - Wiley Online Library
… properties of photodegraded melanin may result from the depletion of its catechol units. This
Photodegradation of eumelanin and pheomelanin and its pathophysiological implications. …

Melanin Biopolymers in Pharmacology and Medicine—Skin Pigmentation Disorders, Implications for Drug Action, Adverse Effects and Therapy

M Karkoszka, J Rok, D Wrześniok - Pharmaceuticals, 2024 - mdpi.com
… However, it should be noted that pheomelanin, unlike eumelanin, undergoes photodegradation
under the influence of UV radiation, resulting in the production of hydrogen peroxide, …

Recent advances and progress on melanin: from source to application

L Guo, W Li, Z Gu, L Wang, L Guo, S Ma, C Li… - International journal of …, 2023 - mdpi.com
… and indole units, with cysteine in its pheomelanin core and eumelanin on its surface [76]. …
Nigrasomes should contain pheomelanin in the core and eumelanin on the surface [77]. …

[HTML][HTML] Photoreactivity and phototoxicity of experimentally photodegraded hair melanosomes from individuals of different skin phototypes

K Mokrzyński, M Sarna, T Sarna - Journal of Photochemistry and …, 2023 - Elsevier
… We also analyzed possible phototoxic effects of photodegraded hair melanosomes of …
Therefore, the conversion of pheomelanin subunits accompanying photodegradation would …

Recent advances in characterization of melanin pigments in biological samples

K Wakamatsu, S Ito - International Journal of Molecular Sciences, 2023 - mdpi.com
… of melanins into three groups: eumelanin (EM), pheomelanin (PM), and allomelanins—the …
ii) describes the application of our methods to study photodegradation of EM and PM, and (iii) …

Understanding the Mechanism of Light-Induced Age-Related Decrease in Melanin Concentration in Retinal Pigment Epithelium Cells

AE Dontsov, MA Yakovleva, AA Vasin, AA Gulin… - International Journal of …, 2023 - mdpi.com
… Table 1 shows the masses responsible for the photodegradation products by melanin in
both the melanosomes and melanolipofuscin granules. The assignments were proposed …

Melanoma, melanin, and melanogenesis: The Yin and Yang relationship

RM Slominski, T Sarna, PM Płonka, C Raman… - Frontiers in …, 2022 - frontiersin.org
… Although eumelanin and pheomelanin derive from the common precursor dopaquinone, …
study, it was demonstrated that partially photodegraded 5-S-cysteinyldopa melanin, which …

… of reactive oxygen species and expression of antioxidant enzymes in human melanocytes correlate with melanin content: implications on the response to solar UV …

PR Upadhyay, RJ Starner, VB Swope, K Wakamatsu… - Antioxidants, 2022 - mdpi.com
It is resistant to photodegradation, and eumelanin–rich melanosomes remain intact … We
quantified the basal eumelanin, pheomelanin, and total melanin contents and compared these …

MelaninThe Éminence Grise of Melanoma and Parkinson's Disease Development

D Krasowska, A Małek, J Kurzepa, L Kapka-Skrzypczak… - Cancers, 2023 - mdpi.com
impact of melanin synthesis on these diseases, considering the divergent roles of
eumelanin and pheomelanin, melanin types present in both skin and brain cells. Additionally, it