… and phytochemicals from the bark of Hypericum roeperianum (Hypericaceae) had strong antibacterial activity and showed synergistic effects with antibiotics against …

OMF Demgne, F Damen, AG Fankam… - Journal of …, 2021 - Elsevier
… The overall results showed a considerable increase of the tested antibiotic activity. The
highest effects were noted with CLO, DOX, and TET in association with HRB at MIC/2 and MIC/4. …

Antibiotic Potentiation Through Phytochemical-Based Efflux Pump Inhibitors to Combat Multidrug Resistance Bacteria

HS Cheema, A Maurya, S Kumar… - Medicinal …, 2024 - ingentaconnect.com
… cal agents that improve an antibiotic's ability to act effectively … ) Overexpression of efflux
pumps to expel antibiotics from the … because of their broadspectrum antibacterial activity [97, 98]. …

Antibacterial Activities and Phytochemical Screening of Crude Extracts from Kenyan Macaranga Species Towards MDR Phenotypes Expressing Effux Pumps

I Hashim, LK Omosa, VA Nchiozem-Ngnitedem… - 2021 - erepository.uonbi.ac.ke
… of antibiotics and consequently their activity.The pathogens used in this work are known for
their ability to express efflux pumps to … The increase in the antibacterial activity of the different …

Phytochemicals with activity against methicillin-resistant Staphylococcus aureus

M Liang, X Ge, H Xua, K Ma, W Zhang, Y Zan, T Efferth… - Phytomedicine, 2022 - Elsevier
… the membrane structure and inhibiting the efflux pump. … Several types of phytochemicals with
antibacterial activity … with synergistic antibacterial activity to antibiotics may inhibit or modify …

[HTML][HTML] Tackling multiple-drug-resistant bacteria with conventional and complex phytochemicals

T Suganya, IASV Packiavathy… - Frontiers in Cellular …, 2022 - frontiersin.org
antibiotics, leading to the development of resistance. Some phytochemicals are reported as
efflux pump … The antimicrobial activity of some phytochemicals against bacterial pathogens is …

[HTML][HTML] Plant-based phytochemicals as possible alternative to antibiotics in combating bacterial drug resistance

HMA AlSheikh, I Sultan, V Kumar, IA Rather… - Antibiotics, 2020 - mdpi.com
… , change in cell permeability, alteration of drug targets, intrinsic expression of efflux pumps
and biofilm formation that acts … This study shows the promising antimicrobial activity from the …

[HTML][HTML] Exploring phytochemicals for combating antibiotic resistance in microbial pathogens

T Khare, U Anand, A Dey, YG Assaraf… - Frontiers in …, 2021 - frontiersin.org
… as well as antibacterial activities, the phytochemicals have … the efflux pump inhibition activity
against the NorA efflux pumps. … bactericidal agents or antimicrobial agents potentiating the …

[HTML][HTML] Plant-derived secondary metabolites as the main source of efflux pump inhibitors and methods for identification

AJ Seukep, V Kuete, L Nahar, SD Sarker… - Journal of pharmaceutical …, 2020 - Elsevier
… are derived from phytochemicals [13]. Phytochemicals may have a direct antimicrobial
effect… Moreover, they can be used to improve the effectiveness of the usual antibiotics after …

Enhancement of the antibiotic activity by quercetin against Staphylococcus aureus efflux pumps

JFS Dos Santos, SR Tintino, ARP da Silva… - Journal of Bioenergetics …, 2021 - Springer
… them act as potentiators of some antibiotics by inhibiting druggrowth and the permanence
in blue the absence of growth. … antibiotic in strains carrying efflux pumps is an indication of …

[HTML][HTML] GC-MS Profile and Enhancement of Antibiotic Activity by the Essential Oil of Ocotea odorífera and Safrole: Inhibition of Staphylococcus aureus Efflux Pumps

RS Almeida, PR Freitas, ACJ Araújo… - Antibiotics, 2020 - mdpi.com
… essential oils, as well as safrole, could modulate bacterial growth in different resistant strains,
this study aims to characterize the phytochemical profile and evaluate the antibacterial and …