Tolllike receptors in neuroinflammation, neurodegeneration, and alcohol‐induced brain damage

M Pascual, M Calvo‐Rodriguez, L Núñez… - IUBMB …, 2021 - Wiley Online Library
… , neuronal death, and cognitive impairment compared to wild-… in ischemic stroke also
contributes to limit brain injury and to … gliosis, neuronal death, demyelination and brain damage. …

A DNA Nanostructure-Based Neuroprotectant against Neuronal Apoptosis via Inhibiting Toll-like Receptor 2 Signaling Pathway in Acute Ischemic Stroke

M Zhou, T Zhang, B Zhang, X Zhang, S Gao, T Zhang… - ACS …, 2021 - ACS Publications
… to reduce brain damage, attenuate neurological deficits, and … reflects the severity of the
ischemic brain injury. To select the … Not only do they play a significant role in protection against …

Effect of Early Inhibition of Toll-Like Receptor 4 on Hippocampal Plasticity in a Neonatal Rat Model of Hypoxic-Ischemic Brain Damage

Q Li, Z Ouyang, Y Zhang, Z Li, X Zhu, Z Tang - Molecular Neurobiology, 2024 - Springer
brain injury that can lead to schizophrenia, attention-deficit … , and other brain damage
factors can alter neuronal dendrite … Perineuronal nets are a vital part of the extracellular matrix, …

The role of Toll-like receptor signaling pathways in cerebrovascular disorders: The impact of spreading depolarization

R Ashayeri Ahmadabad, M Khaleghi Ghadiri… - Journal of …, 2020 - Springer
… Under ischemic conditions, ischemic-induced mediators … signaling pathway in early brain
injury following SAH [131]. … play an important role in vasospasm and neuronal apoptosis after …

[HTML][HTML] Early Toll-like receptor 4 inhibition improves immune dysfunction in the hippocampus after hypoxic-ischemic brain damage

Z Xing, T Zhen, F Jie, Y Jie, L Shiqi, Z Kaiyi… - … Journal of Medical …, 2022 - ncbi.nlm.nih.gov
… plays an important role in brain development, damage and … an important pattern recognition
receptor (PRR) on nerve cell … directly involved in neuronal functional impairment after HIBD. …

[HTML][HTML] Roles of neuronal toll-like receptors in neuropathic pain and central nervous system injuries and diseases

C Acioglu, RF Heary, S Elkabes - Brain, Behavior, and Immunity, 2022 - Elsevier
deficiency throughout embryonic development. Embryonic TLR2 deficiency might provoke
neural … the impairment of spatial learning and memory. The involvement of TLR2 in cognitive …

Toll-like receptor 4 signaling in neurons mediates cerebral ischemia/reperfusion injury

L Liu, TC Xu, ZA Zhao, NN Zhang, J Li… - Molecular Neurobiology, 2023 - Springer
… involved in neuronal damage and functional deficits in a … are believed to play a crucial role
in ischemic injury [33, 34], we … potential neuroprotective therapy for ischemic brain damage. …

Toll-like receptor 4 signaling in focal cerebral ischemia: a focus on the neurovascular unit

BM Famakin, R Vemuganti - Molecular neurobiology, 2020 - Springer
… -mediated secondary brain damage after stroke [4]. Inhibition or deficiency of TLR4 was …
neuronal function following focal cerebral ischemia. Specifically, in a study of the course of …

[HTML][HTML] Role of astroglial toll-like receptors (TLRs) in central nervous system infections, injury and neurodegenerative diseases

L Li, C Acioglu, RF Heary, S Elkabes - Brain, behavior, and immunity, 2021 - Elsevier
… The goal of the current review is to highlight the essential roles … are involved in the crosstalk
between glia and neurons and … In the injured and ischemic brain, degenerated axons and …

Toll-like receptor-mediated neuroinflammation: relevance for cognitive dysfunctions

S Squillace, D Salvemini - Trends in pharmacological sciences, 2022 - cell.com
… in brain physiology as well as in peripheral and central … more efficient drugs for the
treatment of cognitive impairment. … of neuronal morphogenesis and brain functions via Toll-like