[HTML][HTML] Placental 13C-DHA metabolism and relationship with maternal BMI, glycemia and birthweight
OC Watkins, P Selvam, R Appukuttan Pillai… - Molecular …, 2021 - Springer
… Cases of known pre-existing type 1 and type 2 diabetes mellitus … , and greater phospholipid
amounts, while fasting glycemia was … the activation of placental secretory phospho-lipase A2 (…
amounts, while fasting glycemia was … the activation of placental secretory phospho-lipase A2 (…
[HTML][HTML] The metabolic response of human trophoblasts derived from term placentas to metformin
JL Tarry-Adkins, IG Robinson, LC Pantaleão… - Diabetologia, 2023 - Springer
… Gene expression and protein analysis were performed using … We show that the specific
triglycerides accumulating within … in the mother [36], although we show that PUFAs accumulate …
triglycerides accumulating within … in the mother [36], although we show that PUFAs accumulate …
[HTML][HTML] The impact of hyperglycemia upon BeWo trophoblast cell metabolic function: A multi-OMICS and functional metabolic analysis
… pre-existing (such as in type 1 DM or type 2 DM) or develops … the glucose-induced
accumulation of triglyceride species that … on placental function through altering gene expression. …
accumulation of triglyceride species that … on placental function through altering gene expression. …
[HTML][HTML] Placental transcriptome profiling in subtypes of diabetic pregnancies is strongly confounded by fetal sex
SM Kedziora, B Obermayer, M Sugulle, F Herse… - International Journal of …, 2022 - mdpi.com
… gene expression signatures related to the diabetic placental … expression patterns are
related to maternal pregnancy … gestational diabetes (GDM), 17 women with type I diabetes …
related to maternal pregnancy … gestational diabetes (GDM), 17 women with type I diabetes …
[HTML][HTML] Leptin as a key regulator of the adipose organ
C Picó, M Palou, CA Pomar, AM Rodríguez… - Reviews in Endocrine …, 2022 - Springer
… as well as mammary gland [16] and placenta [17] ̵ with long-… (or OBR) gene and belongs
to the cytokine class 1 family [44]… of triglyceride lipase (ATGL), the principal lipase at the initial …
to the cytokine class 1 family [44]… of triglyceride lipase (ATGL), the principal lipase at the initial …
Maternal diet disrupts the placenta–brain axis in a sex-specific manner
… if triglyceride accumulation in the placenta could serve as a proxy for … of gene expression
with maternal triglyceride accumulation revealed a strong dimorphic trend in gene expression. …
with maternal triglyceride accumulation revealed a strong dimorphic trend in gene expression. …
[HTML][HTML] Human Placental Adaptive Changes in Response to Maternal Obesity: Sex Specificities
ED Santos, MH Hernández, V Sérazin… - International Journal of …, 2023 - mdpi.com
… Maternal circulating triglycerides (TGs) are first broken down into FFAs by placental lipases
(ie, lipoprotein lipase and … that female fetuses have larger amounts of adipose tissue. Male …
(ie, lipoprotein lipase and … that female fetuses have larger amounts of adipose tissue. Male …
Early pregnancy dyslipidemia is associated with placental DNA methylation at loci relevant for cardiometabolic diseases
M Ouidir, X Zeng, T Workalemahu, D Shrestha… - …, 2020 - Future Medicine
… DNA methylation levels at the lipoprotein lipase (LPL) gene … lipids and deposit large amounts
of triglycerides in hepatocytes (… evidence for associations of maternal high triglycerides with …
of triglycerides in hepatocytes (… evidence for associations of maternal high triglycerides with …
Perinatal lipid nutrition
AI Leikin-Frenkel - Molecular Nutrition: Mother and Infant, 2021 - Elsevier
… released triacylglycerol is substrate for the placental lipase … and posttranscriptional
regulation of gene expression. The … lipid accumulation in the placenta by either an increased FA …
regulation of gene expression. The … lipid accumulation in the placenta by either an increased FA …
[HTML][HTML] Pathophysiological insight into fatty acid-binding protein-4: multifaced roles in reproduction, pregnancy, and offspring health
Y Shi, CC Wang, L Wu, Y Zhang, A Xu… - International Journal of …, 2023 - mdpi.com
… hormone-sensitive lipase (HSL) and adipose triglyceride lipase (ATGL… , and gene expression
in the placenta for substantial … with type 1 diabetes also demonstrated a significantly higher …
in the placenta for substantial … with type 1 diabetes also demonstrated a significantly higher …