… is unable to pass through pores of the plant cell wall (35–50 nm) [… by the fusion of cocaine
hydrolase (a huBChE mutant … proteins designed as native analogues, including improved half-…

… mutagenesis was used to design NCS variants with the aim … that the catalytic efficiency of
butyrylcholinesterase (BchE, an … plant-derived natural products are currently being developed…

… recombinant enzyme was designed and produced using … For instance, plant-derived BChE,
created problems due to … to function with elevated hydrolase activity and also slowing down …

… ACHE variants with catalytic activity include synaptic ACHE (ACHE… Novel classes of
CHT-specific inhibitors have been developed. … Huperzine A supply relies on natural plant sources …

… in vivo, selective ligands and antibodies have been developed to address this question. It
could be shown, that a heteromer selective antibody can enhance the effect of [d-Pen2,5]-…

… effects on aquatic animals and plants. More importantly, it is … and developed based on human
BChE or bacterial cocaine … mutated butyrylcholinesterase treatment for cocaine addiction, …

… better predict interactions or interpret toxicological findings of these different groups of SC we
conducted initial activity … successfully approved using thebacon as suitable test compound. …

… plants’ recreational use, mechanism of actions and toxicities. Relevant published documents
on psychoactive plants … Therefore, the present review defines psychoactive plants as plants …

… Through various advents in chemistry, efforts have been made … to acetylcholinesterase or
butyrylcholinesterase surged over … PON1 variants with a broad spectrum of activity against a …

… that can effectively modulate activity and stability. … Cocaine Hydrolase Variants of
Butyrylcholinesterase Used in This … on an enzyme system plant-derived cocaine hydrolase …