… mainly responsible for Ca 2+ removal and PMCA4 acts primarily as a signaling molecule in
the … β-adrenergic stimulation can initiate neural nitric oxide synthase (nNOS) activity and NO …

… of the Ca 2+ signalling machinery. Among these proteins, … calcineurin, the endothelial nitric
oxide synthase (eNOS) and … calcium regulation, only tumour cell-specific PMCA4 targeting …

… Evidence suggests that plasma membrane Ca2+ ATPases (PMCAs), … It was hypothesized
that plasma membrane (PM) associated … The current thesis highlights the relevance of PMCA4 …

… PMCA4, leading to perturbations in intracellular calcium levels 17 . ATA was utilized to investigate
the involvement of PMCA4 in endothelial cell … by calcineurin/NFAT signaling 18 . While …

… of ATPase Ca ++ transporting plasma membrane 4 (PMCA4) in … 3B, minimal florescence
signal was observed in the testis … It was previously reported that PMCA4 and the nitric oxide …

… ATPase pumps (the plasma membrane calcium ATPase pump (PMCA) and the sodiumpotassium
ATPase … that due to the importance of complex intracellular calcium oscillations in the …

… and ubiquitous calcium (Ca2+)-sensing protein that coordinates signal transduction through
… An important set of targets for CaM are the nitric oxide synthase (NOS) isozymes. NOS …

… disrupted Ca2+ signalling and cell death through mitochondrial … of CFTR and PMCA4 on
the apical plasma membrane of HPOs … To function properly, the ATPase PMCA4 relies on ATP …

… using expressed genes in Ca 2+ signaling and TGF-β … (eg, progesterone, prostacyclin, nitric
oxide, and relaxin) that serve … as plasma membrane calcium ATPase isoform 4, PMCA4) and …

… signaling complexes are found in the plasma membrane (PM), the … of cell signaling and
communication within signaling … 1997a), whereas the PMCA4 that respond to agonist stimulation …