SGLT2 inhibition and uric acid excretion in patients with type 2 diabetes and normal kidney function

DLS Suijk, MJB van Baar… - Clinical Journal of the …, 2022 - journals.lww.com
… excretion, and hemodynamic kidney function were measured … Second, in the Uric Acid
Excretion study, ten people with … , plasma uric acid has been linked to glomerular hypertension …

Uric acid, Cardiovascular Function, and the Kidney

V Kurra - 2022 - trepo.tuni.fi
… dietary 2% oxonic acid (inhibitor of uric acid degrading uricase-… have been suggested to
cause glomerular vascular disease, … Plasma uric acid concentration and hemodynamic variables …

Serum uric acid levels and cardiometabolic profile in middle-aged, treatment-naïve hypertensive patients

P Theofilis, V Tsimihodimos, A Vordoni… - High Blood Pressure & …, 2022 - Springer
… UA levels were correlated with male sex, waist circumference, estimated glomerular filtration
rate (eGFR), serum calcium and insulin levels, as well as with fractional excretion of UA. A …

Serum uric acid and kidney disease measures independently predict cardiovascular and total mortality: the uric acid right for heart health (URRAH) project

E Russo, F Viazzi, R Pontremoli… - Frontiers in …, 2021 - frontiersin.org
… of unfavorable outcome only at serum concentration greater than what … kidney clearance,
uric acid perpetuates glomerular injury, … , and changes in glomerular hemodynamics leading to …

Hyperuricaemia and gout in cardiovascular, metabolic and kidney disease

C Borghi, E Agabiti-Rosei, RJ Johnson… - European journal of …, 2020 - Elsevier
… , the negative effects of serum uric acid are independent on the decrease in glomerular filtration
… xanthine oxidase, was not associated with improvements in haemodynamic parameters, …

The prognostic impact of serum uric acid on disease severity and 5-year mortality in patients with idiopathic pulmonary artery hypertension

L Yan, Z Huang, Z Zhao, Q Zhao, Y Tang… - Frontiers in …, 2022 - frontiersin.org
serum UA levels and hemodynamic parameters, and analyze the prognostic impact of baseline
hyperuricemia and the variability of serum … of the pre-glomerular arteries and proliferation …

Acute and chronic effects of SGLT2 inhibitor empagliflozin on renal oxygenation and blood pressure control in nondiabetic normotensive subjects: a randomized …

A Zanchi, M Burnier, ME Muller… - Journal of the …, 2020 - Am Heart Assoc
… salutary hemodynamic effects on the heart in people with … term slowing of estimated
glomerular filtration rate decline and … effects on systolic blood pressure 29 and plasma uric acid

Management of hyperuricemia in patients with chronic kidney disease: a focus on renal protection

JT Kielstein, R Pontremoli, M Burnier - Current Hypertension Reports, 2020 - Springer
… ), plasma uric acid levels are increased because of the decrease in glomerular filtration rate.
… in rat models, intrarenal hemodynamic parameters have also been examined in humans, …

Effects of empagliflozin on estimated extracellular volume, estimated plasma volume, and measured glomerular filtration rate in patients with heart failure (Empire HF …

J Jensen, M Omar, C Kistorp, C Tuxen… - The lancet Diabetes & …, 2021 - thelancet.com
… Secondary prespecified outcome measures were plasma concentration of uric acid,
UACR, and HbA 1c . Secondary exploratory outcomes were haemoglobin; haematocrit; …

Comparison of the effect of uric acid/albumin ratio on coronary slow flow with other inflammation-based markers

K Toprak, K Özen, T Memioğlu, M İnanır… - Biomarkers in …, 2024 - Taylor & Francis
… ; those who were hemodynamically unstable; and those … The estimated glomerular filtration
rate was calculated using … dividing the serum uric acid level by the serum albumin level. …