The immunosuppressive effect of the endocannabinoid system on the inflammatory phenotypes of macrophages and mesenchymal stromal cells: a comparative study
T Ruhl, C Corsten, JP Beier, BS Kim - Pharmacological Reports, 2021 - Springer
… Succesful polarization was detected by secreted soluble … and exhibited a typical
spindle-shaped morphology (Fig. 1a). … , but no cannabinoid compound affected the production of …
spindle-shaped morphology (Fig. 1a). … , but no cannabinoid compound affected the production of …
Protein interactors and trafficking pathways that regulate the cannabinoid type 1 receptor (CB1R)
A Fletcher-Jones, KL Hildick, AJ Evans… - Frontiers in molecular …, 2020 - frontiersin.org
… Endocannabinoid system signaling downstream of CB1R is … This review focuses on the
trafficking and polarized surface … the ER, intracellular CB1R is detected in the axon as soon as 25 …
trafficking and polarized surface … the ER, intracellular CB1R is detected in the axon as soon as 25 …
Cannabinoid and planar cell polarity signaling converges to direct placentation
YS Kim, Y Li, J Yuan, JP Borg… - Proceedings of the …, 2021 - National Acad Sciences
… endocannabinoids via G protein–coupled cannabinoid … The PCP pathway is best known
for its role in cell polarization at the … to CRE expression patterns, CRE activity was detected in …
for its role in cell polarization at the … to CRE expression patterns, CRE activity was detected in …
[HTML][HTML] The endocannabinoid system in the visual process
SJ Pasquaré, E Chamorro-Aguirre… - Journal of Photochemistry …, 2023 - Elsevier
… (cAMP) production is a characteristic response of cannabinoid … In mice retina, DAGLα was
detected in OFF bipolar cells type 1 … This figure shows how cannabinoid-related enzymes and …
detected in OFF bipolar cells type 1 … This figure shows how cannabinoid-related enzymes and …
[HTML][HTML] Cannabinoids regulate sensory processing in early olfactory and visual neural circuits
T Heinbockel, A Straiker - Frontiers in neural circuits, 2021 - frontiersin.org
… , the endogenous cannabinoids or endocannabinoids, also … The authors found a THC effect
on both olfactory detection thresholds and … polarization, subsequent changes in calcium and …
on both olfactory detection thresholds and … polarization, subsequent changes in calcium and …
Endocannabinoid signaling in brain diseases: Emerging relevance of glial cells
A Bernal‐Chico, V Tepavcevic, A Manterola, C Utrilla… - Glia, 2023 - Wiley Online Library
… and cellular hallmarks of endocannabinoid signaling in glial … MAGL and FAAH have also
been detected at the intracellular … of cannabinoid receptors and classical endocannabinoids …
been detected at the intracellular … of cannabinoid receptors and classical endocannabinoids …
Imaging the endocannabinoid signaling system
… receptor of endocannabinoids, the cannabinoid type-1 … mechanisms that may shape their
nanoscale distribution … , GRAB sensors revolutionized the detection of bioactive compounds in …
nanoscale distribution … , GRAB sensors revolutionized the detection of bioactive compounds in …
Enantiomeric Agonists of the Type 2 Cannabinoid Receptor Reduce Retinal Damage during Proliferative Vitreoretinopathy and Inhibit Hyperactive Microglia In Vitro
AP Young, AM Szczesniak, K Hsu… - ACS Pharmacology & …, 2024 - ACS Publications
… The endocannabinoid system (ECS) contributes broadly to the physiology of animals and is
… could detect activation, blockade, and inverse agonism in a sensitive manner (Figure S5). …
… could detect activation, blockade, and inverse agonism in a sensitive manner (Figure S5). …
Design and function of targeted endocannabinoid nanoparticles
… to cannabinoid receptor 1 (CB 1 ) and cannabinoid receptor … birefringence via cross-polarizing
optical microscopy (POM) … C and the scattered light was detected at a scattering angle of …
optical microscopy (POM) … C and the scattered light was detected at a scattering angle of …
Genetic deletion of the cannabinoid receptors CB1 and CB2 enhances inflammation with diverging effects on skin wound healing in mice
T Ruhl, EF Lippold, T Christer, B Schaefer, BS Kim… - Life Sciences, 2021 - Elsevier
… The endocannabinoid system is ascribed great significance … to detect surface expression
levels of both cannabinoid … Although it does not directly induce macrophage polarization, …
levels of both cannabinoid … Although it does not directly induce macrophage polarization, …