[HTML][HTML] Failure of achieving tacrolimus target blood concentration might be avoided by a wide genotyping of transplanted patients: evidence from a retrospective study
G Pallio, N Irrera, A Bitto, F Mannino, L Minutoli… - Journal of personalized …, 2020 - mdpi.com
… on genetic polymorphisms and CYP3A5 polymorphisms differently … in the gene that encodes
for CYP3A4 is a polymorphism … The SNP in exon 26 (C3435T) is in strict imbalance with two …
for CYP3A4 is a polymorphism … The SNP in exon 26 (C3435T) is in strict imbalance with two …
[HTML][HTML] Impact of polymorphisms in transporter and metabolizing enzyme genes on olanzapine pharmacokinetics and safety in healthy volunteers
… Thus, the objective of this candidate-gene study was to investigate the effect of 72
polymorphisms in 21 genes on olanzapine pharmacokinetics and safety, including transporters (eg …
polymorphisms in 21 genes on olanzapine pharmacokinetics and safety, including transporters (eg …
Evaluation of genetic polymorphisms associated with the metabolic effects of aripiprazole and olanzapine
D Koller - 2020 - digital.csic.es
… The influence of polymorphisms on weight and lipid metabolism .............................................
159 6.4. HEPATIC PERFORMANCE..........................................................................................................…
159 6.4. HEPATIC PERFORMANCE..........................................................................................................…
[HTML][HTML] Reviewing pharmacogenetics to advance precision medicine for opioids
L Magarbeh, I Gorbovskaya, B Le Foll, R Jhirad… - Biomedicine & …, 2021 - Elsevier
… and, to a lesser extent, OPRM1 polymorphism in personalized opioid drug dosing. As a result,
… ABCB1 C3435T No significant differences among ABCB1 subgroups with regards of pain …
… ABCB1 C3435T No significant differences among ABCB1 subgroups with regards of pain …
[HTML][HTML] Genetic variations associated with pharmacoresistant epilepsy
N Cárdenas‑Rodríguez… - Molecular …, 2020 - spandidos-publications.com
… 2A (ACSM2A) gene polymorphisms with serum alanine … ) indicating that these gene
polymorphisms can be used to … Germany, Spain and the United States, it was reported that the …
polymorphisms can be used to … Germany, Spain and the United States, it was reported that the …
[HTML][HTML] SLCO1B1 phenotype and CYP3A5 polymorphism significantly affect atorvastatin bioavailability
P Zubiaur, MD Benedicto, G Villapalos-García… - Journal of Personalized …, 2021 - mdpi.com
… and by the Spanish Drugs Agency (AEMPS). Complying with Spanish and European …
Another ABCB1 haplotype was inferred by exclusively considering C3435T, G2677T/A and …
Another ABCB1 haplotype was inferred by exclusively considering C3435T, G2677T/A and …
Association of ABCB1 and VEGFA gene polymorphisms with breast cancer susceptibility and prognosis
A Madrid-Paredes, MÁ Casado-Combreras… - … -Research and Practice, 2020 - Elsevier
… The purpose of this study was to evaluate the association between these gene polymorphisms
… were determined in 84 cases of BC and 119 controls of South Spanish Caucasian origin. …
… were determined in 84 cases of BC and 119 controls of South Spanish Caucasian origin. …
[HTML][HTML] Genetic polymorphisms associated with rheumatoid arthritis development and antirheumatic therapy response
DS Mikhaylenko, MV Nemtsova, IV Bure… - International journal of …, 2020 - mdpi.com
… genes polymorphisms are associated with etanercept and infliximab sensitivity according to
the results of GWAS in Spain … Fc-γ receptor type 2A gene polymorphisms are also associated …
the results of GWAS in Spain … Fc-γ receptor type 2A gene polymorphisms are also associated …
[HTML][HTML] Insights into the pharmacogenetics of tacrolimus pharmacokinetics and pharmacodynamics
M Brunet, M Pastor-Anglada - Pharmaceutics, 2022 - mdpi.com
… More recently, several genetic polymorphisms in selected SLC and ABC transporter … C3435T,
it has been unequivocally demonstrated that this SNP is associated with decreased MDR1 …
it has been unequivocally demonstrated that this SNP is associated with decreased MDR1 …
[HTML][HTML] A pharmacogenetically guided acenocoumarol dosing algorithm for Chilean patients: A discovery cohort study
A Roco, E Nieto, M Suárez, M Rojo… - Frontiers in …, 2020 - frontiersin.org
… single nucleotide polymorphisms (SNPs) (Table 1) with acenocoumarol dosage. … Spanish
model included the non-genetic variables sex, age, BMI, and initial INR value, and the genetic …
model included the non-genetic variables sex, age, BMI, and initial INR value, and the genetic …