Clinical utility of ABCB1 single nucleotide polymorphism on tacrolimus dose requirements in Egyptian liver transplant patients

AAE Saab, ES El-hadidi, MM Hussein… - Egyptian Liver …, 2021 - Springer
… rejection among adult Caucasian Spanish liver transplant recipients. In … main
immunosuppressant did not appear to be related to the donor or recipient ABCB1 3435C>T …

Race and genetics versus 'race'in genetics: a systematic review of the use of African ancestry in genetic studies

TM Duello, S Rivedal, C Wickland… - Evolution, medicine, and …, 2021 - academic.oup.com
… In the 71 studies, polymorphisms were determined to be in equilibrium or excluded if they …
than in Spaniards and other white populations and higher than in Central Americans, Asians …

Olanzapine Use in Schizophrenia and the Modulation of Its Response by Genetic Variations

S Salman, SMA Halimi, I Khan - Molecular Medicine …, 2022 - rootspress.org
… the ABCB1 C3435T polymorphism (S… polymorphism had a greater response to olanzapine
therapy have speculated that the ABCB1 G2677T and C3435T MDR1 genetic polymorphisms

[PDF][PDF] Association of genetic polymorphisms on methotrexate toxicity in patients with rheumatoid arthritis

MJZ Romero, MMM Montoro… - Archives of …, 2020 - archivesofmedicalscience.com
polymorphisms can play a part in inter-individual differences in toxicity. Our aim is therefore
to determine the influence of gene polymorphisms … on these polymorphisms in 200 patients …

Beyond Single Nucleotide Polymorphisms: CYP3A5367 Composite and ABCB1 Haplotype Associations to Tacrolimus Pharmacokinetics in Black and White …

DA Brazeau, K Attwood, CJ Meaney, GE Wilding… - … in Genetics, 2020 - frontiersin.org
… nucleotide polymorphisms: 1236C > T (rs1128503), 2677G > T/A(rs2032582), and 3435C
> T(rs1045642). Finally, a combined analysis using both CYP3A5 and ABCB1 polymorphisms

Pharmacometric Evaluation of the Clinical Impact of Genetic Polymorphisms of the Cytochrome P450 and P-Glycoprotein in the Pharmacokinetics and …

PRM Magalhães - 2020 - estudogeral.uc.pt
genetic and non-genetic factors were identified as potential determining causes of these
findings. Specifically, a high frequency of genetic polymorphisms and … genes. Apart from these …

Clinically relevant pharmacogenetic markers in Tatars and Balkars

SP Abdullaev, KB Mirzaev, IS Burashnikova… - Molecular Biology …, 2020 - Springer
… following gene polymorphisms were found between both ethnic groups in respect of different
markers and with Russians. Our study shows differences in prevalence of the main relevant …

Influence of genetic polymorphisms on pharmacokinetics and treatment response of mycophenolic acid: a scoping review

HY Yow, M Ikawati, S Siswanto, A Hermawan… - …, 2024 - Future Medicine
This scoping review explores the impact of genetic polymorphisms on the pharmacokinetics
and treatment responses of mycophenolic acid (MPA), an immunosuppressant. The study …

Impact of genetic factors on platinum-induced gastrointestinal toxicity

Y Zheng, Z Deng, M Tang, D Xiao, P Cai - Mutation Research/Reviews in …, 2020 - Elsevier
… The influence of gene polymorphisms in the platinum pathway on GI toxicity has been
extensively analyzed. Variations in study sample size, ethnicity, design, treatment schedule, dosing…

Atremorine in Parkinson's disease: From dopaminergic neuroprotection to pharmacogenomics

R Cacabelos, I Carrera, O Martínez… - Medicinal Research …, 2021 - Wiley Online Library
polymorphisms (SNPs) in 22 pathogenic genes (Table 3) encoding for proteins associated
with PD and a novel panel of 113 SNPs and 3 copy number variations (CNVs) in 60 genes