Beyond Single Nucleotide Polymorphisms: CYP3A5367 Composite and ABCB1 Haplotype Associations to Tacrolimus Pharmacokinetics in Black and White …

DA Brazeau, K Attwood, CJ Meaney, GE Wilding… - … in Genetics, 2020 - frontiersin.org
… nucleotide polymorphisms: 1236C > T (rs1128503), 2677G > T/A(rs2032582), and 3435C
> T(rs1045642). Finally, a combined analysis using both CYP3A5 and ABCB1 polymorphisms

Atremorine in Parkinson's disease: From dopaminergic neuroprotection to pharmacogenomics

R Cacabelos, I Carrera, O Martínez… - Medicinal Research …, 2021 - Wiley Online Library
polymorphisms (SNPs) in 22 pathogenic genes (Table 3) encoding for proteins associated
with PD and a novel panel of 113 SNPs and 3 copy number variations (CNVs) in 60 genes

Cannabis pharmacogenomics: a path to personalized medicine

M Babayeva, ZG Loewy - Current Issues in Molecular Biology, 2023 - mdpi.com
… and cannabis dependence and schizophrenia in the SpanishC3435T polymorphism was
studied in heavy cannabis users [330]. It was estimated that the ABCB1 C3435T polymorphism

CYP3A5 influences oral tacrolimus pharmacokinetics and timing of acute kidney injury following allogeneic hematopoietic stem cell transplantation

ND Seligson, X Zhang, MC Zemanek… - Frontiers in …, 2024 - frontiersin.org
… Introduction: Polymorphisms in genes responsible for the metabolism and transport of
tacrolimus have been demonstrated to influence clinical outcomes for patients following …

[HTML][HTML] Current perspectives on interethnic variability in multiple myeloma: Single cell technology, population pharmacogenetics and molecular signal transduction

M Gandhi, V Bakhai, J Trivedi, A Mishra… - Translational …, 2022 - Elsevier
… Similarly, single nucleotide polymorphisms in specific genes … correlation of SNPs of MDR1
gene and haplotype variants … of genotypes and alleles in MDR1 loci (C3435T, C1236T and …

Impact of genetic factors on platinum-induced gastrointestinal toxicity

Y Zheng, Z Deng, M Tang, D Xiao, P Cai - Mutation Research/Reviews in …, 2020 - Elsevier
… The influence of gene polymorphisms in the platinum pathway on GI toxicity has been
extensively analyzed. Variations in study sample size, ethnicity, design, treatment schedule, dosing…

Vincristine-induced peripheral neuropathy in childhood acute lymphoblastic leukemia: genetic variation as a potential risk factor

QY Yang, YH Hu, HL Guo, Y Xia, Y Zhang… - Frontiers in …, 2021 - frontiersin.org
… Recently, genetic polymorphisms of the ABCB1 gene and their effects on the … A meta-analysis
for the Spanish subgroup revealed a significant increased risk of VIPN in childhood ALL …

Pharmacogenetics and precision medicine approaches for the improvement of COVID-19 therapies

M Biswas, N Sawajan, T Rungrotmongkol… - Frontiers in …, 2022 - frontiersin.org
… conducted in Spain reported the … C3435T ABCB1 SNP may be at risk of hyperbilirubinemia
and severe jaundice as well. Numerous studies showed that certain genetic polymorphisms

Genetic overlap between temporomandibular disorders and primary headaches: A systematic review

D Cruz, F Monteiro, M Paço, M Vaz-Silva… - … Dental Science Review, 2022 - Elsevier
genes seemed to be not associated with the risk for migraine in Caucasian Spanish people;
… COMT gene’s polymorphisms were proved to be a major influence in the studies focused on …

The Role of Global and Local Ancestry on Clopidogrel Response in African Americans

G Yang, C Alarcon, P Friedman, L Gong… - … 2023: Kohala Coast …, 2022 - World Scientific
… African Americans may be useful in identifying potential genesPolymorphisms of KDR gene
are associated with coronary … ABCB1 C3435T polymorphism and response to clopidogrel …