Population pharmacokinetics of piperacillin and tazobactam in critically ill patients receiving extracorporeal membrane oxygenation: an ASAP ECMO study

V Cheng, MH Abdul-Aziz, F Burrows… - Antimicrobial Agents …, 2021 - Am Soc Microbiol
receiving ECMO (23). The aims of this paper were to describe the population PK of
piperacillin and tazobactam in critically ill adults receiving ECMO with and without RRT and to …

Pharmacokinetics of piperacillin and tazobactam in critically Ill patients treated with continuous kidney replacement therapy: A mini‐review and population …

DJ Selig, JP DeLuca, KK Chung… - Journal of Clinical …, 2022 - Wiley Online Library
… commonly prescribed to critically ill patients placed on … pharmacokinetic data in critically ill
patients undergoing CKRT to better understand pharmacokinetics of pip-tazo in this population

Population pharmacokinetics of piperacillin following continuous infusion in critically ill patients and impact of renal function on target attainment

V Klastrup, A Thorsted, M Storgaard… - Antimicrobial agents …, 2020 - Am Soc Microbiol
… The aim of this study was to assess the PK of piperacillin in critically ill patients treated
with CI. A population PK model was developed to identify patient covariates and evaluate the …

Population pharmacokinetics and dosing optimization of piperacillin-tazobactam in critically ill patients on extracorporeal membrane oxygenation and the influence of …

J Hahn, KL Min, S Kang, S Yang, MS Park… - Microbiology …, 2021 - Am Soc Microbiol
… therapy (CRRT), may alter the pharmacokinetics of piperacillin-tazobactam. We aimed to …
a population pharmacokinetic model of piperacillin-tazobactam in critically ill patients during …

Population pharmacokinetics of piperacillin/tazobactam in critically ill Korean patients and the effects of extracorporeal membrane oxygenation

YK Kim, HS Kim, S Park, H Kim… - Journal of …, 2022 - academic.oup.com
… of both piperacillin and tazobactam in critically ill patients. … population PK model of
piperacillin/tazobactam that is suitable for critically ill Korean adult patients, including those receiving

A population pharmacokinetics and pharmacodynamic approach to optimize tazobactam activity in critically ill patients

SN Kalaria, M Gopalakrishnan… - Antimicrobial agents and …, 2020 - Am Soc Microbiol
… was to characterize tazobactam PK in a cohort of critically ill patients with Gram… population
PK modeling approach. Currently, a population model that characterizes the pharmacokinetics

Piperacillin-tazobactam in intensive care units: a review of population pharmacokinetic analyses

I El-Haffaf, JA Caissy, A Marsot - Clinical pharmacokinetics, 2021 - Springer
piperacillin-tazobactam and provides comprehensive data on current dosing strategies while
identifying significant covariates in critically ill patients… care unit OR critically ill). Additionally…

Using a validated population pharmacokinetic model for dosing recommendations of continuous infusion piperacillin for critically ill adult patients

I El-Haffaf, R Guilhaumou, L Velly, A Marsot - Clinical Pharmacokinetics, 2022 - Springer
… Six models were evaluated with a dataset consisting of 30 critically ill patients (35 samples)
receiving piperacillin by continuous infusion. Models were subject to prediction-based (bias …

Population pharmacokinetics of continuous infusion of piperacillin/tazobactam in very elderly hospitalized patients and considerations for target attainment against …

PG Cojutti, E Morandin, M Baraldo, F Pea - International journal of …, 2021 - Elsevier
… PIP concentrations between 200 and 300 mg/L up to 60 h after treatment initiation have
been documented in a prospective study conducted among 18 critically ill patients treated with …

Population pharmacokinetics of piperacillin/tazobactam across the adult lifespan

M Hemmersbach-Miller, SJ Balevic, PL Winokur… - … pharmacokinetics, 2023 - Springer
… adults, a dedicated PK study for piperacillin/tazobactam is indicated to optimize dosing. …
a population PK modeling approach to quantify how the systemic CL of piperacillin/tazobactam