Insight on Cardiac Chronobiology and Latest Developments of Chronotherapeutic Antihypertensive Interventions for Better Clinical Outcomes

K Joshi, M Das, A Sarma, MK Arora… - … Hypertension …, 2023 - ingentaconnect.com
between the waking and sleeping treatment groups. In the Hygia Chronotherapy Trial, both
… of melatonin receptors. Administration of melatonin or melatonin agonists can potentially

Toward precision medicine: circadian rhythm of blood pressure and chronotherapy for hypertension-2021 NHLBI workshop report

ML Gumz, D Shimbo, M Abdalla, RC Balijepalli… - …, 2023 - Am Heart Assoc
Hypertension or high blood pressure (BP) is among the most … Additional potential interventions
not discussed at the … dipping status in hypertensive patients, 203 and melatonin, which …

[HTML][HTML] Evidence for the benefits of melatonin in cardiovascular disease

M Tobeiha, A Jafari, S Fadaei, SMA Mirazimi… - Frontiers in …, 2022 - frontiersin.org
… distributed the rats between five groups: no treatment control, … The results revealed that
blood pressure treatment without … chronotherapy. Different types of brain hormones, such as …

Circadian rhythms of risk factors and management in atherosclerotic and hypertensive vascular disease: Modern chronobiological perspectives of an ancient disease

YJ Geng, MH Smolensky, O Sum-Ping… - Chronobiology …, 2023 - Taylor & Francis
… through chronotherapeutic control of atherogenic/hypertensive … and hypertension) is
maintained through balance between … dim light condition, while melatonin levels were similar in …

Chronotherapy

DP Cardinali, GM Brown, SR Pandi-Perumal - Handbook of Clinical …, 2021 - Elsevier
… chronobiotic medications, such as melatonin, that affect the output … an actively driven fluid
exchange between para-arterial and … Blood pressure is at its lowest during the sleep cycle and …

Circadian rhythm in hypertension: Bibliometrics and knowledge mapping from 1990 to 2022

Z Peng, Y Tan, X Zou, X Zhang - Chronobiology International, 2024 - Taylor & Francis
… and chronotherapy with antihypertensive treatments for … citations focused on the relationship
between sleep, BP rhythm, … Melatonin is a hormone derived from the pineal gland that has …

Cardiovascular diseases: a therapeutic perspective around the clock

AC Soares, DA Fonseca - Drug Discovery Today, 2020 - Elsevier
… Then, we discuss the utility of chronotherapy in the context of CVD … hypertension and
coronary artery disease, has opened the discussion on the potential use of exogenous melatonin

[HTML][HTML] Nighttime administration of antihypertensive medication: a review of chronotherapy in hypertension

HJ Kim, SH Jo - The Korean Journal of Internal Medicine, 2024 - ncbi.nlm.nih.gov
potential solution: the emerging concept of chronotherapy in … , and the use of melatonin
agonists highlight the essential role of … of chronotherapy on hypertension, specifically among shift …

Recent advances in circadian-regulated pharmacokinetics and its implications for chronotherapy

F Yu, Y Liu, R Zhang, L Zhu, T Zhang, Y Shi - Biochemical Pharmacology, 2022 - Elsevier
… , enzyme activity, and renal function, among others. It is well … Transcutaneous administration
of melatonin achieves higher … antagonist used in treatment of hypertension and angina) …

Diabetes and atherothrombosis: The circadian rhythm and role of melatonin in vascular protection

A Otamas, PJ Grant, RA Ajjan - Diabetes and Vascular …, 2020 - journals.sagepub.com
… Studies have shown associations between melatoninpotential of melatonin comes from
evidence of melatonin deficiency … and hypertension-induced injury to the endothelial cell layer. …