Anhedonia as a central factor in depression: Neural mechanisms revealed from preclinical to clinical evidence
S Wang, F Leri, SJ Rizvi - Progress in Neuro-Psychopharmacology and …, 2021 - Elsevier
… of reward deficits in the context of depression, and has implicated … anhedonia, and medications
targeting these systems may also potentially normalize reward processing in depression. …
targeting these systems may also potentially normalize reward processing in depression. …
Characterizing anhedonia: A systematic review of neuroimaging across the subtypes of reward processing deficits in depression
A Borsini, ASJ Wallis, P Zunszain, CM Pariante… - Cognitive, Affective, & …, 2020 - Springer
… Moreover, faster attenuation of NAc activity has been … the neurobiology of anhedonia in MDD;
anhedonia was conceptualized as … in response to unexpected losses or negative feedback. …
anhedonia was conceptualized as … in response to unexpected losses or negative feedback. …
Toward a better understanding of the mechanisms and pathophysiology of anhedonia: are we ready for translation?
DA Pizzagalli - American Journal of Psychiatry, 2022 - Am Psychiatric Assoc
… of major depressive disorder (MDD), anhedonia is reported … the ventral striatum, with
potentiated DA transmission in the VTA … that underlie anhedonia and reward processing …
potentiated DA transmission in the VTA … that underlie anhedonia and reward processing …
Neural Correlates of Anhedonia in Major Depressive Disorder: Insights from Concurrent Analysis of Feedback-Related Negativity and Stimulus-Preceding Negativity
Y Sun, Z Huang, X Gao, L Chen, J Wang… - Neuropsychiatric …, 2023 - Taylor & Francis
… anhedonia and reward processing deficits in MDD. Ultimately, this research will provide
important information for identifying reliable neural markers that may aid in diagnostic …
important information for identifying reliable neural markers that may aid in diagnostic …
Anhedonia in depression and bipolar disorder
AE Whitton, DA Pizzagalli - Anhedonia: Preclinical, Translational, and …, 2022 - Springer
… anhedonia/reward processing predicts response to a specific treatment or the persistence of
depressive … ACC, and OFC, as well as potentiated activation in various PFC regions (medial …
depressive … ACC, and OFC, as well as potentiated activation in various PFC regions (medial …
Cooperative synaptic and intrinsic plasticity in a disynaptic limbic circuit drive stress-induced anhedonia and passive coping in mice
… Conversely, D2-MSN excitability was attenuated in stressed … and potentiated onto D1-MSNs,
and this potentiated VH → … improvement in depressive and anhedonic symptoms together …
and this potentiated VH → … improvement in depressive and anhedonic symptoms together …
Anhedonia, hyperkatifeia, and negative reinforcement in substance use disorders
GF Koob - Anhedonia: preclinical, translational, and clinical …, 2022 - Springer
… as the potentiated intensity of negative emotional/… drug taking makes anhedonia worse
during the process of seeking … of despair (eg, depressive symptoms and suicidal ideation) and …
during the process of seeking … of despair (eg, depressive symptoms and suicidal ideation) and …
[PDF][PDF] Anhedonia and its intervention in depressive adults: New developments based on Research Domain Criteria (RDoC) in mental illnesses
J Mao, J Yuan - Stress and Brain, 2021 - acrlab.cn
… , as the mainstream theory of anhedonia in depression, and also emphasize the … processing
in the pathogenesis of anhedonia. Furthermore, to reinstate reward processing in depressed …
in the pathogenesis of anhedonia. Furthermore, to reinstate reward processing in depressed …
Environmental contributions to anhedonia
KL Harkness, SJ Lamontagne… - Anhedonia: Preclinical …, 2021 - Springer
… processing as a crucial mechanism underlying anhedonia in … of endogenous depression,
which includes anhedonia as a … , controllable stress may potentiate incentive motivation and …
which includes anhedonia as a … , controllable stress may potentiate incentive motivation and …
Anhedonia in anxiety disorders
CT Taylor, SN Hoffman, AJ Khan - Anhedonia: Preclinical, translational …, 2022 - Springer
… Evidence supporting the link between anhedonia and … in depression (see chapter “Anhedonia
in Depression and Bipolar … reward processing phase, at least in part driven by anhedonia …
in Depression and Bipolar … reward processing phase, at least in part driven by anhedonia …