Eosinophilic inflammation in COPD: from an inflammatory marker to a treatable trait

B David, M Bafadhel, L Koenderman, A De Soyza - Thorax, 2021 - thorax.bmj.com
… satisfactorily to long-acting inhaled bronchodilator(s). In … the assessment of patients, risk
prediction, treatment guidance and … to patients with airway eosinophils of >3% with stable COPD.…

Advances in inhaled corticosteroids for the treatment of chronic obstructive pulmonary disease: what is their value today?

M Cazzola, J Ora, L Calzetta, P Rogliani… - Expert Opinion on …, 2022 - Taylor & Francis
… count (BEC), which predicts the magnitude of the effect of … ICS to long-acting bronchodilators
in patients with COPD and … process even in patients with stable COPD [Citation40]. In …

Lipid profile and atherogenic indices in patients with stable chronic obstructive pulmonary disease

I Markelić, I Hlapčić, D Rogić, I Rako… - Nutrition, Metabolism …, 2021 - Elsevier
… in sera of patients with stable COPD and their associations … ), long-acting β 2 agonist (LABA)
or long-acting muscarinic … In addition, we wanted to evaluate predictive performance of lipid …

How can the findings of the EMAX trial on long-acting bronchodilation in chronic obstructive pulmonary disease be applied in the primary care setting?

EM Kerwin, PW Jones, LH Bjermer… - Chronic Respiratory …, 2023 - journals.sagepub.com
… In a post hoc economic analysis of EMAX data using the validated GALAXY model, UMEC/VI
was predicted to be the most cost-effective treatment option versus either monotherapy …

[HTML][HTML] Influence of disease severity, smoking status and therapy regimes on leukocyte subsets and their ratios in stable chronic obstructive pulmonary disease

I Hlapčić, AV Dugac, S Popović-Grle… - Archives of Medical …, 2022 - ncbi.nlm.nih.gov
… are often combined with long-acting bronchodilators. To the … to assess their performances
in stable COPD due to the already … Can we predict the prognosis of COPD with a routine blood …

Severity distribution and treatment of chronic obstructive pulmonary disease in China: baseline results of an observational study

T Yang, B Cai, B Cao, J Kang, F Wen, Y Chen… - Respiratory …, 2022 - Springer
… In order to include patients with stable COPD at enrolment, … Overall, long-acting bronchodilators
were more widely used … eosinophil counts to predict better response to ICS therapy. …

Clinical utilization of airway inflammatory biomarkers in the prediction and monitoring of clinical outcomes in patients with chronic obstructive pulmonary disease

D Yehia, C Leung, DD Sin - Expert Review of Molecular …, 2024 - Taylor & Francis
… In stable COPD patients, an elevated NLR is associated with … long-acting muscarinic antagonist
(LAMA), and a long-acting … and COPD patients with a significant bronchodilator response …

COPD‐X Australian guidelines for the diagnosis and management of chronic obstructive pulmonary disease: 2022 update

E Dabscheck, J George, K Hermann… - Medical Journal of …, 2022 - Wiley Online Library
… maintenance long-acting bronchodilator therapy, except in people … be considered in people
with stable COPD and hypercapnia (… A history of COPD exacerbations is the best predictor of …

Prevalence, diagnostic utility and associated characteristics of bronchodilator responsiveness

R Beasley, R Hughes, A Agusti, P Calverley… - American journal of …, 2024 - atsjournals.org
bronchodilators (BDs) alone, whereas in patients with COPD, long-acting muscarinic antagonists
or long-acting β… was lower for COPD, whereas for ΔFVC >10% predicted, the proportion …

Experimental drugs in clinical trials for COPD: artificial intelligence via machine learning approach to predict the successful advance from early-stage development to …

L Calzetta, E Pistocchini, A Chetta… - Expert Opinion on …, 2023 - Taylor & Francis
COPD include bronchodilators, mainly long-acting muscarinic receptor antagonists (LAMA)
and long-acting … for the management of most stable COPD patients will remain anchored to …